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非骨水泥型与骨水泥型全膝关节置换术的强化改善及相当的生存率:患者报告结局的2年分析及植入物生存率的5年分析

Enhanced improvement and comparable survivorship in cementless versus cemented total knee arthroplasty: a 2-year analysis of patient reported outcomes and 5-year analysis of implant survivorship.

作者信息

Pasqualini Ignacio, Huffman Nickelas, Khan Shujaa, Zielinski Matthew, Elmenawi Khaled A, Shen Jianhua, Hampp Emily, Masini Michael, Noble John, Bhowmik-Stoker Manoshi, Piuzzi Nicolas

机构信息

Cleveland Clinic, Cleveland, USA.

Stryker (United States), Kalamazoo, USA.

出版信息

Eur J Orthop Surg Traumatol. 2025 May 28;35(1):220. doi: 10.1007/s00590-025-04318-0.

Abstract

PURPOSE

This study aimed to evaluate patient-reported outcomes, functional recovery, satisfaction, and implant survivorship for cementless and cemented TKA.

METHODS

A prospective, non-randomized, multicenter study was conducted on 453 patients. Cohort 1 (n = 373 knees) received a fully cementless construct with the Triathlon Tritanium Tibial Baseplate, Triathlon Tritanium Patella, Triathlon CR or PS Beaded Femur with Peri-Apatite, and the Triathlon Tibial Insert. Cohort 2 (n = 147 knees) received a fully cemented construct with identical implant design. Oxford Knee Score (OKS), 2011 Knee Society Score (KSS), and Short Form 12 scores were recorded preoperatively and at 6 weeks, 6 months, 1 year, and 2 years postoperatively. Implant survivorship and adverse events were also recorded.

RESULTS

OKS (mean difference [MD] 1.5, p = 0.0123), KSS Symptoms for pain (with level walking [MD 0.62, p = 0.0007]; with stairs or incline [MD 0.85, p = 0.0037), KSS Patient satisfaction (MD 2.31, p = 0.0004), and KSS Functional Activities (MD 0.53, p = 0.0108) were significantly greater in Cohort 1 out to 2 years postoperatively. The Kaplan-Meier estimated all-cause survivorship was 98.2% (95% CI: 95.7-99.3%) for Cohort 1 and 97.5% (95% CI: 92.6-99.2%) for Cohort 2 (p = 0.4366).

CONCLUSION

Cementless TKA exhibited similar or greater patient outcomes, satisfaction, and function up to 2 years postoperative, while both cohorts showed comparable rates of adverse events and survivorship at 5-year follow-up. This evidence underscores the clinical value and safety of cementless TKA.

摘要

目的

本研究旨在评估非骨水泥型和骨水泥型全膝关节置换术(TKA)患者报告的结局、功能恢复情况、满意度及植入物生存率。

方法

对453例患者进行了一项前瞻性、非随机、多中心研究。队列1(n = 373膝)接受了完全非骨水泥型假体组合,包括Triathlon Tritanium胫骨基板、Triathlon Tritanium髌骨、带有磷灰石涂层的Triathlon CR或PS带珠股骨假体以及Triathlon胫骨衬垫。队列2(n = 147膝)接受了相同植入物设计的完全骨水泥型假体组合。术前及术后6周、6个月、1年和2年记录牛津膝关节评分(OKS)、2011年膝关节协会评分(KSS)和简短健康调查问卷12项评分(Short Form 12)。还记录了植入物生存率和不良事件。

结果

术后2年,队列1的OKS(平均差值[MD] 1.5,p = 0.0123)以及KSS疼痛症状评分(平路行走时[MD 0.62,p = 0.0007];上下楼梯或斜坡时[MD 0.85,p = 0.0037])、KSS患者满意度评分(MD 2.31,p = 0.0004)和KSS功能活动评分(MD 0.53,p = 0.0108)均显著更高。队列1的Kaplan-Meier估计全因生存率为98.2%(95%置信区间:95.7 - 99.3%),队列2为97.5%(95%置信区间:92.6 - 99.2%)(p = 0.4366)。

结论

非骨水泥型TKA在术后2年显示出相似或更好的患者结局、满意度和功能,而两个队列在5年随访时不良事件发生率和生存率相当。这一证据强调了非骨水泥型TKA的临床价值和安全性。

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