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髋部骨折患者手术前后生活质量的比较评估:一项前瞻性纵向观察研究。

Comparative Assessment of Quality of Life in Hip Fracture Patients Before and After Surgery: A Prospective Longitudinal Observational Study.

作者信息

Căpăstraru Bogdan Florin, Levai Codrina Mihaela, Mederle Ovidiu Alexandru, Velimirovici Milan Daniel, Folescu Roxana, Bogdan Hogea, Prejbeanu Radu, Vlad Silviu Valentin

机构信息

Doctoral School, Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.

Research Center for Medical Communication, Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.

出版信息

Healthcare (Basel). 2025 May 12;13(10):1126. doi: 10.3390/healthcare13101126.

DOI:10.3390/healthcare13101126
PMID:40427963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12111009/
Abstract

Hip fractures are a leading cause of morbidity in the elderly, often resulting in declining physical function, psychological distress, and diminished quality of life (QoL). This study aimed to evaluate changes in QoL among hip fracture patients preoperatively and postoperatively, comparing diverse patient subgroups to identify factors influencing recovery. We conducted a prospective longitudinal observational study at Victor Babeș University of Medicine and Pharmacy Timișoara, recruiting 77 adult patients admitted for surgical management of hip fractures between March 2023 and March 2025. Standardized questionnaires, including the Short Form-36 (SF-36), World Health Organization Quality of Life (WHOQOL-BREF), Hospital Anxiety and Depression Scale (HADS), and Generalized Anxiety Disorder-7 (GAD-7), were administered preoperatively and at 3 months postoperatively. Demographic, clinical, and surgical variables were also recorded. Participants' mean age was 72.6 years (SD 8.1), with 57.1% female. Postoperative QoL scores (SF-36 Physical Function domain mean 52.7 ± 9.2) improved significantly compared to preoperative scores (44.8 ± 8.7, = 0.012). WHOQOL-BREF physical and psychological domain scores similarly increased ( < 0.05). Anxiety and depression symptoms, as measured by HADS and GAD-7, decreased markedly postoperatively in most subgroups. Subgroup analyses revealed that patients undergoing total hip arthroplasty demonstrated more pronounced QoL improvements than those receiving partial hip replacement. Older patients (≥80 years) exhibited improvements but at a slower rate. Quality of life indicators show notable improvement following surgical treatment of hip fractures, underscoring the significance of timely orthopedic intervention and comprehensive perioperative care. Anxiety and depression levels also declined, highlighting the benefits of a structured follow-up. These findings may guide clinicians toward optimizing patient-centered recovery protocols and targeted interventions, particularly for older adults or those with high baseline anxiety and depression levels.

摘要

髋部骨折是老年人发病的主要原因,常导致身体功能下降、心理困扰和生活质量(QoL)降低。本研究旨在评估髋部骨折患者术前和术后QoL的变化,比较不同患者亚组以确定影响恢复的因素。我们在蒂米什瓦拉维克托·巴比什医科药科大学进行了一项前瞻性纵向观察研究,招募了2023年3月至2025年3月期间因髋部骨折接受手术治疗的77名成年患者。术前和术后3个月使用标准化问卷,包括简明健康状况调查问卷(SF-36)、世界卫生组织生活质量量表(WHOQOL-BREF)、医院焦虑抑郁量表(HADS)和广泛性焦虑障碍量表(GAD-7)。还记录了人口统计学、临床和手术变量。参与者的平均年龄为72.6岁(标准差8.1),女性占57.1%。术后QoL评分(SF-36身体功能领域平均分为52.7±9.2)与术前评分(44.8±8.7,P = 0.012)相比有显著改善。WHOQOL-BREF身体和心理领域评分同样增加(P<0.05)。大多数亚组中,通过HADS和GAD-7测量的焦虑和抑郁症状术后明显减轻。亚组分析显示,接受全髋关节置换术的患者QoL改善比接受部分髋关节置换术的患者更显著。老年患者(≥80岁)有改善但速度较慢。髋部骨折手术治疗后生活质量指标显示出显著改善,强调了及时骨科干预和全面围手术期护理的重要性。焦虑和抑郁水平也有所下降,突出了结构化随访的益处。这些发现可能指导临床医生优化以患者为中心的康复方案和有针对性的干预措施,特别是对于老年人或基线焦虑和抑郁水平较高的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b072/12111009/1c908dd4f0a7/healthcare-13-01126-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b072/12111009/1c908dd4f0a7/healthcare-13-01126-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b072/12111009/1c908dd4f0a7/healthcare-13-01126-g001.jpg

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本文引用的文献

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Nurs Rep. 2025 Feb 26;15(3):78. doi: 10.3390/nursrep15030078.
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Impact and Prevalence of Depression and Anxiety in Rheumatoid Arthritis-A Cross-Sectional Study with Self-Reported Questionnaires.类风湿关节炎中抑郁和焦虑的影响及患病率——一项使用自填式问卷的横断面研究
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