Akgül Mustafa Şakir, Uysal Hüseyin Şahin, Keskin Nevin Köremezli, Çetin Tuğba, Başdemirci Merve, Akgül Melike Nur, Yıldız Zehra, Çiftçi Ebubekir, Soslu Recep
Department of Coaching Education, Hasan Dogan Faculty of Sport Sciences, Karabuk University, Karabuk 78000, Turkey.
Department of Physical Education and Sport, Faculty of Sport Sciences, Burdur Mehmet Akif Ersoy University, Burdur 15030, Turkey.
Medicina (Kaunas). 2025 Apr 26;61(5):804. doi: 10.3390/medicina61050804.
This study compared the effects of blood flow restriction resistance exercise (BFR-RE) and high-load resistance exercise (HL-RE) in voluntary exhaustion on quadriceps muscle adaptations in untrained young males. This study used a randomized controlled design that included 30 untrained young males (age = 21.42 ± 2.51). The BFR-RE group performed leg extension exercises with 60% occlusion pressure and 30% of one maximum repetition in volitional exhaustion. The same exercise was conducted at 70% 1RM in the HL-RE group. Fourteen variables were used to evaluate the intervention efficacy, including muscle thickness, stiffness, strength, cross-sectional area (CSA), and subcutaneous fat thickness. Analyses were reported using frequentist and Bayesian approaches. The Bayes factor (BF10 and BFincl) was interpreted based on negative and positive values. The results revealed that the main effect of time was statistically significant for muscle strength, thickness, CSA, and stiffness ( < 0.05, BFincl > 1) and, in intragroup comparisons, both groups showed improvements in these parameters ( < 0.05, BF10 > 1). A statistically significant decrease in subcutaneous fat thickness was observed in the BFR-RE group ( < 0.05, BF10 > 1), while this change was not observed in the HL-RE group ( > 0.05, BF10 < 1). Similarly, a statistically significant increase in right rectus femoris muscle stiffness was detected in the BFR-RE group ( < 0.05, BF10 > 1) but not in the HL-RE group ( > 0.05, BF10 < 1). Furthermore, time's main effect was statistically insignificant for thigh circumference ( > 0.05, BFincl < 1). The group × time interaction was statistically significant only for peak power leg flexion left ( < 0.05, BFincl > 1), and a statistically significant difference in favor of the BFR-RE group was observed in the intergroup comparisons ( < 0.05, BF10 > 1). In conclusion, BF-RE exercise with voluntary exhaustion may be as effective as HL-RE for hypertrophic adaptations in untrained young males.
本研究比较了血流限制抗阻运动（BFR-RE）和高负荷抗阻运动（HL-RE）在力竭状态下对未经训练的年轻男性股四头肌适应性的影响。本研究采用随机对照设计，纳入30名未经训练的年轻男性（年龄=21.42±2.51）。BFR-RE组在力竭状态下以60%的闭塞压力和1次最大重复量的30%进行腿部伸展运动。HL-RE组以70%的1RM进行相同的运动。使用14个变量评估干预效果，包括肌肉厚度、硬度、力量、横截面积（CSA）和皮下脂肪厚度。分析采用频率学派和贝叶斯方法进行报告。贝叶斯因子（BF10和BFincl）根据负值和正值进行解释。结果显示，时间的主效应在肌肉力量、厚度、CSA和硬度方面具有统计学意义（P<0.05，BFincl>1），在组内比较中，两组在这些参数上均有改善（P<0.05，BF10>1）。BFR-RE组皮下脂肪厚度有统计学意义的下降（P<0.05，BF10>1），而HL-RE组未观察到这种变化（P>0.05，BF10<1）。同样，BFR-RE组右侧股直肌肌肉硬度有统计学意义的增加（P<0.05，BF10>1），而HL-RE组未观察到（P>0.05，BF10<1）。此外，时间的主效应在大腿围方面无统计学意义（P>0.05，BFincl<1）。组×时间交互作用仅在左侧腿部屈曲峰值功率方面具有统计学意义（P<0.05，BFincl>1），在组间比较中观察到有利于BFR-RE组的统计学显著差异（P<0.05，BF10>1）。总之，力竭状态下的BF-RE运动对未经训练的年轻男性的肥大适应性可能与HL-RE一样有效。
