Labunet Anca, Objelean Adriana, Kui Andreea, Rusu Laura, Vigu Alexandra, Sava Sorina
Dental Materials Discipline, Department 4-Prosthodontics and Dental Materials, Faculty of Dental Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Prosthetic Dentistry Discipline, Department 4-Prosthodontics and Dental Materials, Faculty of Dental Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Medicina (Kaunas). 2025 May 1;61(5):837. doi: 10.3390/medicina61050837.
: Menopause is a natural physiological process involving hormone production changes, affecting many functions and systems. This scoping review offers a contemporary outlook on oral issues related to menopause, such as saliva production, periodontal and alveolar bone issues, and changes in the microbiome, and it also investigates the effects of hormonal therapy. A literature search from 2019 to 2024 was conducted according to PRISMA-ScR guidelines. Articles investigating the oral effects of menopause were included. : A total of 30 studies were covered; 8 focused on salivary alterations, 5 on periodontal issues, 7 on bone, 3 on the microbiome, and 7 on multiple oral problems, showing that xerostomia and altered taste are the most common oral manifestations, followed by indirect causal effects on periodontitis. Many of these alterations can be contained through regular consultations and adequate hygiene. Some alveolar bone changes may occur after menopause and are associated with osteoporosis. : Postmenopausal women experience notable reductions in salivary flow, pH levels, and taste sensitivity, which are associated with hormonal fluctuations as well as factors such as age, medication use, and treatments for climacteric symptoms. This population is at increased risk for periodontitis, tooth loss, altered taste, lichen planus, candidiasis, and decreased bone mineral density, which also affect the peri-implant area. Osteoporosis and hormonal changes can play a significant role in causing these increased risks. Maintaining proper oral hygiene and consistently monitoring bone health are essential. While changes in the oral microbiome are more heavily influenced by reductions in salivary flow than by menopause itself, hormone therapy may help improve periodontal health by reducing harmful bacteria and fostering a more balanced microbial environment. The intricate impact of hormones on oral health highlights the necessity for further research.
绝经是一个涉及激素分泌变化的自然生理过程,会影响多种功能和系统。本综述对与绝经相关的口腔问题提供了当代观点,如唾液分泌、牙周和牙槽骨问题以及微生物群变化,并研究了激素疗法的效果。根据PRISMA-ScR指南进行了2019年至2024年的文献检索。纳入了研究绝经对口腔影响的文章。共涵盖30项研究;8项关注唾液改变,5项关注牙周问题,7项关注骨骼,3项关注微生物群,7项关注多种口腔问题,结果表明口干和味觉改变是最常见的口腔表现,其次是对牙周炎的间接因果影响。其中许多改变可通过定期咨询和适当的口腔卫生得到控制。绝经后可能会发生一些牙槽骨变化,并与骨质疏松症有关。绝经后女性的唾液流量、pH值水平和味觉敏感性显著降低,这与激素波动以及年龄、药物使用和更年期症状治疗等因素有关。该人群患牙周炎、牙齿脱落、味觉改变、扁平苔藓、念珠菌病和骨密度降低的风险增加,这些也会影响种植体周围区域。骨质疏松症和激素变化在导致这些风险增加方面可能起重要作用。保持适当的口腔卫生并持续监测骨骼健康至关重要。虽然口腔微生物群的变化受唾液流量减少的影响比绝经本身更大,但激素疗法可能通过减少有害细菌和促进更平衡的微生物环境来帮助改善牙周健康。激素对口腔健康的复杂影响凸显了进一步研究的必要性。