Mahale Swapna A, Dhadse Prasad, Thosar Sumedha, Bhandari Vedant, Patil Akhil, Syed Sadatullah, Bapat Ranjeet Ajit, Chaubal Tanay, Eusufzai Sumaiya Zabin, Abullais Shahabe Saquib
Department of Periodontology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education & Research, Wardha 442001, India.
Department of Periodontology, MGV's KBH Dental College and Hospital, Nashik 422003, India.
Medicina (Kaunas). 2025 May 16;61(5):905. doi: 10.3390/medicina61050905.
: Periodontal regeneration involves techniques intended at restoring the lost supporting tissue around a periodontally weakened tooth. These regenerative methods frequently utilize periosteal grafts to stimulate the evolvement of vital adjacent tissues. This paper intended to evaluate the use of autogenous periosteal grafts in treating grade II furcation defects (Glickman Classification 1953) in patients with chronic periodontitis. : The databases MEDLINE (via PubMed), Cochrane, EBSCO, and Google Scholar were searched for papers published in English from January 1991 till December 2022. Three individuals examined the reclaimed articles according to the inclusion norms. Randomized controlled trials (RCTs) assessing the efficacy of autogenous periosteal grafts for treating Grade II furcation defects in chronic periodontitis patients were involved. Only four related studies were identified for data extraction, involving 80 patients aged 18 to 52 years. Outcome variables measured included horizontal bone loss (HD), vertical bone loss (VD), pocket depth (PD), clinical attachment level (CAL), bone height (BH), gingival recession (GR), plaque index (PI), and gingival index (GI). Data were examined using RevMan 5.4.1 software. Mean differences and 95% confidence intervals were employed to estimate effect sizes. : Both groups showed similar results for reductions in PI, GI, and BOP. However, The periosteal graft also yielded better outcomes for CAL gain, BH, and GR. The meta-analysis showed a significant overall effect of Periosteal Barrier Membrane (PBM) on horizontal and vertical bony change levels, but subgroup differences between unilateral and bilateral applications were not statistically significant due to high heterogeneity. Although the bilateral subgroup demonstrated significant benefits of PBM treatment, the overall findings across the clinical attachment level group remain inconclusive. Current evidence suggests that while PBM may benefit bilateral mandibular sites, and autogenous periosteal grafts offer no added advantage over OFD alone in Grade II furcation defects, the overall findings remain inconclusive.
牙周再生涉及旨在恢复牙周组织薄弱牙齿周围丧失的支持组织的技术。这些再生方法经常利用骨膜移植物来刺激重要相邻组织的发育。本文旨在评估自体骨膜移植物在治疗慢性牙周炎患者Ⅱ度根分叉病变（Glickman 1953年分类）中的应用。：检索MEDLINE（通过PubMed）、Cochrane、EBSCO和谷歌学术数据库，查找1991年1月至2022年12月以英文发表的论文。三名研究人员根据纳入标准对检索到的文章进行审查。纳入评估自体骨膜移植物治疗慢性牙周炎患者Ⅱ度根分叉病变疗效的随机对照试验（RCT）。仅确定四项相关研究进行数据提取，涉及80名年龄在18至52岁的患者。测量的结果变量包括水平骨丧失（HD）、垂直骨丧失（VD）、牙周袋深度（PD）、临床附着水平（CAL）、骨高度（BH）、牙龈退缩（GR）、菌斑指数（PI）和牙龈指数（GI）。使用RevMan 5.4.1软件检查数据。采用平均差和95%置信区间来估计效应大小。：两组在PI、GI和探诊出血（BOP）降低方面显示出相似结果。然而，骨膜移植物在CAL增加、BH和GR方面也产生了更好的结果。荟萃分析显示骨膜屏障膜（PBM）对水平和垂直骨变化水平有显著的总体效应，但由于异质性高，单侧和双侧应用之间的亚组差异无统计学意义。虽然双侧亚组显示PBM治疗有显著益处，但临床附着水平组的总体结果仍无定论。目前的证据表明，虽然PBM可能对双侧下颌部位有益，且在Ⅱ度根分叉病变中自体骨膜移植物单独使用骨膜下翻瓣术（OFD）并无额外优势，但总体结果仍无定论。
