Placide Rick, Reznicek Julie
Department of Orthopedic Surgery, VCU Health, Medical College of Virginia, Richmond, VA 23298-0153, USA.
Division of Infectious Diseases, VCU Health, Medical College of Virginia, Richmond, VA 23298-0153, USA.
J Clin Med. 2025 May 15;14(10):3477. doi: 10.3390/jcm14103477.
Spondylodiscitis is a devastating invasive infection that can lead to debilitating pain, motor weakness, or paralysis, even with appropriate medical and surgical treatment. Over the past two decades, there has been a worldwide increase in the incidence of spondylodiscitis, which can be attributed to a higher prevalence of various risk factors including intravenous drug use, hemodialysis, and spinal surgeries. The lumbar spine is the most likely region to be affected, with being the predominant pathogen. Management of spondylodiscitis requires a multi-disciplinary approach, with close coordination between the spinal surgeon and the infectious diseases specialist. Clinicians should become familiar with the epidemiology and presentation of patients with suspected spondylodiscitis because timely diagnosis and treatment may lead to improved outcomes. This unique review incorporates the perspectives from infectious disease and spine surgery specialists.
脊椎椎间盘炎是一种严重的侵袭性感染，即使经过适当的药物和手术治疗，也可能导致使人衰弱的疼痛、运动无力或瘫痪。在过去二十年中，脊椎椎间盘炎的发病率在全球范围内有所上升，这可归因于包括静脉注射吸毒、血液透析和脊柱手术在内的各种风险因素的较高流行率。腰椎是最易受影响的部位， 是主要病原体。脊椎椎间盘炎的管理需要多学科方法，脊柱外科医生和传染病专家之间要密切协调。临床医生应熟悉疑似脊椎椎间盘炎患者的流行病学和临床表现，因为及时诊断和治疗可能会改善预后。这篇独特的综述纳入了传染病和脊柱外科专家的观点。
