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中华人民共和国城市地区癫痫的流行病学

Epidemiology of epilepsy in urban areas of the People's Republic of China.

作者信息

Li S C, Schoenberg B S, Wang C C, Cheng X M, Zhou S S, Bolis C L

出版信息

Epilepsia. 1985 Sep-Oct;26(5):391-4. doi: 10.1111/j.1528-1157.1985.tb05669.x.

DOI:10.1111/j.1528-1157.1985.tb05669.x
PMID:4043008
Abstract

To determine the prevalence of major neurologic disorders, a door-to-door survey was conducted in six cities of the People's Republic of China during 1983 in a well-defined population of 63,195. The survey included a complete census and a screening interview together with an examination having high sensitivity for detecting individuals with frequently occurring neurologic disorders, including epilepsy. All individuals with responses or findings suggesting neurologic disease were examined by senior neurologists using standardized diagnostic criteria. There was 100% cooperation among the study subjects. Two hundred eighty-nine individuals alive on prevalence day (January 1, 1983) were identified as having epilepsy, yielding a lifetime age-adjusted (to the 1960 U.S. population) point prevalence ratio of 4.4/1,000. There were 16 people who developed epilepsy in the sample population during 1982, providing an age-adjusted incidence rate of 35/100,000 per year. The most frequent type identified was generalized convulsive seizures. Brain injury, intracranial infection, and cerebrovascular disease, in that order, were the leading putative causes of epilepsy.

摘要

为确定主要神经系统疾病的患病率,1983年在中国六个城市对明确界定的63195人进行了挨家挨户的调查。该调查包括全面普查、筛查访谈以及对包括癫痫在内的常见神经系统疾病患者具有高灵敏度的检查。所有有反应或检查结果提示神经系统疾病的个体均由资深神经科医生依据标准化诊断标准进行检查。研究对象的合作率达100%。在患病率调查日(1983年1月1日)存活的289人被确定患有癫痫,经年龄调整(以1960年美国人口为标准)后的终生患病率为4.4/1000。1982年样本人群中有16人患癫痫,经年龄调整后的发病率为每年35/100000。最常见的癫痫类型为全身性惊厥发作。脑损伤、颅内感染和脑血管疾病依次是癫痫的主要假定病因。

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