Rojkiewicz Marcin, Kuś Piotr, Jampilek Josef, Bąk Andrzej, Kozik Violetta
Institute of Chemistry, University of Silesia, 9 Szkolna Street, 40-006 Katowice, Poland.
Department of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 842 15 Bratislava, Slovakia.
Molecules. 2025 May 16;30(10):2182. doi: 10.3390/molecules30102182.
In this study, two isomeric cathinone derivatives, -butyl-norbutylone and -ethylhexylone, seized on the illicit drug market in Poland, were described and characterized by various instrumental analytical methods. The compounds were characterized by electrospray ionization mass spectrometry, high-resolution mass spectrometry, gas chromatography-mass spectrometry, and nuclear magnetic resonance spectroscopy. The two investigated compounds were confirmed as 1-(2-1,3-benzodioxol-5-yl)-2-(butylamino)butan-1-one and 1-(2-1,3-benzodioxol-5-yl)-2-(ethylamino)hexane-1-one, both of which were cathinone derivatives available on the new psychoactive substances (NPS) market. The obtained analytical data should be useful for forensic and toxicological purposes for quick and reliable compound identification.
在本研究中，对在波兰非法毒品市场查获的两种同分异构卡西酮衍生物——β-丁基去甲伪麻黄碱和β-乙基己基酮，采用各种仪器分析方法进行了描述和表征。通过电喷雾电离质谱、高分辨率质谱、气相色谱-质谱和核磁共振光谱对这些化合物进行了表征。所研究的两种化合物被确认为1-(2-1,3-苯并二氧杂环戊烯-5-基)-2-(丁基氨基)丁烷-1-酮和1-(2-1,3-苯并二氧杂环戊烯-5-基)-2-(乙基氨基)己烷-1-酮，这两种都是新精神活性物质（NPS）市场上可获得的卡西酮衍生物。所获得的分析数据应有助于法医和毒理学目的的快速可靠化合物鉴定。
