肿瘤侵袭脑组织的新影像学表现：“瘤周高强化信号”
New imaging findings of tumor invasion into brain tissue: "Peritumoral Hyperintense Enhancement Sign".
作者信息
Mao Xinyi, Li Jianye, Zheng Xuejun, Wang Yujun, Gao Jie, Fu Chunlong, Li Xin, Liang Ming, Wang Xiangping, Qiu Tiantian, Du Haijun, Xue Chen, Liu Yufeng
机构信息
Department of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Zhejiang Chinese Medical University, Hangzhou, China.
出版信息
Front Hum Neurosci. 2025 May 13;19:1592543. doi: 10.3389/fnhum.2025.1592543. eCollection 2025.
INTRODUCTION
This study investigated the MRI characteristics of meningiomas and brain metastases, exploring the relationship between the "Peritumoral Hyperintense Enhancement Sign" and brain invasion, and its clinical implications for treatment planning.
METHODS
A multicenter retrospective analysis was conducted on 24 cases (17 brain metastases and 7 meningiomas), examining the MRI features of the "Peritumoral Hyperintense Enhancement Sign" and corresponding histopathological characteristics.
RESULTS
All cases demonstrated peritumoral enhancement: 8 cases exhibited flame-shaped enhancement, 12 showed crescentic enhancement, and 4 displayed both patterns. Histopathological analysis confirmed brain invasion in regions showing abnormal enhancement.
CONCLUSION
The "Peritumoral Hyperintense Enhancement Sign" not only serves as a valuable indicator of brain invasion and provides guidance for clinical target delineation in treatment planning, but also facilitates more precise treatment planning and may contribute to improved prognostic assessment and reduced recurrence risk.
引言
本研究调查了脑膜瘤和脑转移瘤的MRI特征，探讨了“瘤周高强化征”与脑侵犯之间的关系及其对治疗计划的临床意义。
方法
对24例病例（17例脑转移瘤和7例脑膜瘤）进行多中心回顾性分析，检查“瘤周高强化征”的MRI特征及相应的组织病理学特征。
结果
所有病例均显示瘤周强化：8例呈火焰状强化，12例呈新月形强化，4例两种强化模式均有。组织病理学分析证实，在显示异常强化的区域存在脑侵犯。
结论
“瘤周高强化征”不仅是脑侵犯的重要指标，为治疗计划中的临床靶区勾画提供指导，还有助于制定更精确的治疗计划，并可能有助于改善预后评估和降低复发风险。
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