• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

搏动性耳鸣作为鼻咽癌幸存者放射性诱导的颈内动脉狭窄的一种表现:一例报告

Pulsatile Tinnitus as a Manifestation of Radiation-Induced Internal Carotid Artery Stenosis in a Nasopharyngeal Carcinoma Survivor: A Case Report.

作者信息

Chen Yun-Chiang, Lu Shiang-Ru, Wang Yi-Chi, Yang Shu-Yu, Hsiao Pei-Chi

机构信息

Department of Physical Medicine and Rehabilitation, Chi Mei Medical Center, Tainan, TWN.

Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung, TWN.

出版信息

Cureus. 2025 May 24;17(5):e84762. doi: 10.7759/cureus.84762. eCollection 2025 May.

DOI:10.7759/cureus.84762
PMID:40433019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12106781/
Abstract

Nasopharyngeal carcinoma (NPC) is prevalent in East and Southeast Asia, with radiotherapy being the primary treatment modality. Carotid artery stenosis is a serious but often overlooked complication of radiotherapy. We present the case of a middle-aged NPC survivor who developed progressive symptoms, including left facial numbness, dysphagia, tongue atrophy, postural dizziness, and pulsatile tinnitus, 18 years after concurrent chemoradiation. Carotid ultrasound revealed high-grade stenosis of the left cervical internal carotid artery. Following carotid stenting, his dizziness and tinnitus resolved. This case illustrates the insidious progression of carotid stenosis after radiotherapy and underscores the importance of early vascular assessment in post-radiation patients with atypical symptoms such as pulsatile tinnitus. Clinicians should maintain a high index of suspicion in at-risk individuals, and physical therapists should adopt precautionary rehabilitation strategies to minimize the risk of vascular complications.

摘要

鼻咽癌(NPC)在东亚和东南亚地区较为常见,放射治疗是主要的治疗方式。颈动脉狭窄是放射治疗的一种严重但常被忽视的并发症。我们报告了一例中年鼻咽癌幸存者的病例,该患者在同步放化疗18年后出现进行性症状,包括左侧面部麻木、吞咽困难、舌萎缩、姿势性头晕和搏动性耳鸣。颈动脉超声显示左侧颈内动脉高度狭窄。在进行颈动脉支架置入术后,他的头晕和耳鸣症状得到缓解。该病例说明了放疗后颈动脉狭窄的隐匿进展,并强调了对有搏动性耳鸣等非典型症状的放疗后患者进行早期血管评估的重要性。临床医生应对高危个体保持高度警惕,物理治疗师应采取预防性康复策略,以尽量降低血管并发症的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/523f/12106781/753923250a23/cureus-0017-00000084762-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/523f/12106781/d223307d9efc/cureus-0017-00000084762-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/523f/12106781/e6beec92c5b8/cureus-0017-00000084762-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/523f/12106781/f4bc0b86f9db/cureus-0017-00000084762-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/523f/12106781/37a842423e6c/cureus-0017-00000084762-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/523f/12106781/753923250a23/cureus-0017-00000084762-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/523f/12106781/d223307d9efc/cureus-0017-00000084762-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/523f/12106781/e6beec92c5b8/cureus-0017-00000084762-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/523f/12106781/f4bc0b86f9db/cureus-0017-00000084762-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/523f/12106781/37a842423e6c/cureus-0017-00000084762-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/523f/12106781/753923250a23/cureus-0017-00000084762-i05.jpg

相似文献

1
Pulsatile Tinnitus as a Manifestation of Radiation-Induced Internal Carotid Artery Stenosis in a Nasopharyngeal Carcinoma Survivor: A Case Report.搏动性耳鸣作为鼻咽癌幸存者放射性诱导的颈内动脉狭窄的一种表现:一例报告
Cureus. 2025 May 24;17(5):e84762. doi: 10.7759/cureus.84762. eCollection 2025 May.
2
Pulsatile tinnitus due to stenosis of the supraclinoid segment of the internal carotid artery: Management with a low-profile self-expanding stent.由于颈内动脉虹吸段狭窄导致的搏动性耳鸣:采用低剖面自膨式支架治疗。
Interv Neuroradiol. 2024 Apr;30(2):293-296. doi: 10.1177/15910199221106036. Epub 2022 Jun 3.
3
Effect of angioplasty and stent placement on sensorineural hearing loss and pulsatile tinnitus in a patient with severe internal carotid artery stenosis.球囊扩张和支架置入术治疗严重颈内动脉狭窄患者的感音神经性聋和搏动性耳鸣的效果。
J Stroke Cerebrovasc Dis. 2022 Nov;31(11):106718. doi: 10.1016/j.jstrokecerebrovasdis.2022.106718. Epub 2022 Sep 16.
4
Pulsatile tinnitus cured by angioplasty and stenting of petrous carotid artery stenosis.经皮颈动脉狭窄血管成形术和支架置入术治愈搏动性耳鸣。
Arch Otolaryngol Head Neck Surg. 1998 Apr;124(4):460-1. doi: 10.1001/archotol.124.4.460.
5
Pulsatile tinnitus and carotid artery dissection.搏动性耳鸣与颈动脉夹层
Auris Nasus Larynx. 2018 Feb;45(1):175-177. doi: 10.1016/j.anl.2016.12.004. Epub 2017 Jan 23.
6
Disappeared pulsatile tinnitus related to petrous segment stenosis of the ICA after relief of the stenosis by stenting.在通过支架置入术缓解颈内动脉岩骨段狭窄后,与该狭窄相关的搏动性耳鸣消失。
Interv Neuroradiol. 2013 Mar;19(1):97-101. doi: 10.1177/159101991301900115. Epub 2013 Mar 4.
7
Pulsatile tinnitus from reversal of flow in an aberrant occipital artery: resolved after carotid artery stenting.异常枕动脉血流逆转导致的搏动性耳鸣:颈动脉支架置入术后症状缓解。
AJNR Am J Neuroradiol. 2009 May;30(5):995-7. doi: 10.3174/ajnr.A1393.
8
Study on carotid artery stenosis after radiotherapy for nasopharyngeal carcinoma.研究鼻咽癌放疗后颈动脉狭窄。
J Cancer Res Clin Oncol. 2024 May 25;150(5):273. doi: 10.1007/s00432-024-05788-1.
9
Case report: Early carotid stent shortening in patient with radiation-induced carotid stenosis.病例报告:放射诱导性颈动脉狭窄患者早期颈动脉支架缩短
Front Neurol. 2023 May 9;14:1184210. doi: 10.3389/fneur.2023.1184210. eCollection 2023.
10
Carotid stenosis prevalence after radiotherapy in nasopharyngeal carcinoma: A meta-analysis.鼻咽癌放疗后颈动脉狭窄的患病率:一项荟萃分析。
Radiother Oncol. 2019 Apr;133:167-175. doi: 10.1016/j.radonc.2018.11.013. Epub 2019 Feb 4.

本文引用的文献

1
Progression rate of radiation-induced carotid stenosis in head and neck cancer survivors after statin treatment: a retrospective cohort study.他汀类药物治疗后头颈部癌症幸存者放射性颈动脉狭窄的进展速度:一项回顾性队列研究。
J Neurol. 2024 May;271(5):2573-2581. doi: 10.1007/s00415-024-12197-4. Epub 2024 Feb 8.
2
Relief of postural orthostatic tachycardia syndrome with chiropractic rehabilitation.整脊康复缓解体位性直立性心动过速综合征
J Family Med Prim Care. 2022 Jul;11(7):4006-4009. doi: 10.4103/jfmpc.jfmpc_2108_21. Epub 2022 Jul 22.
3
Impact of radiotherapy for nasopharyngeal carcinoma on carotid stenosis risk: a meta-analysis.
鼻咽癌放疗对颈动脉狭窄风险的影响:一项荟萃分析。
Braz J Otorhinolaryngol. 2022 Nov-Dec;88 Suppl 4(Suppl 4):S98-S107. doi: 10.1016/j.bjorl.2022.03.001. Epub 2022 Mar 21.
4
Ischemic stroke secondary to self-inflicted carotid sinus massage: a case report.因自我施行颈动脉窦按摩导致的缺血性脑卒中:一例报告。
J Med Case Rep. 2021 Feb 23;15(1):83. doi: 10.1186/s13256-021-02680-1.
5
Late side effects of radiation treatment for head and neck cancer.头颈部癌放射治疗的晚期副作用。
Radiat Oncol J. 2020 Jun;38(2):84-92. doi: 10.3857/roj.2020.00213. Epub 2020 Jun 25.
6
Prevalence of carotid stenosis following radiotherapy for head and neck cancer: A systematic review and meta-analysis.头颈部癌放疗后颈动脉狭窄的患病率:一项系统评价和荟萃分析。
Head Neck. 2020 May;42(5):1077-1088. doi: 10.1002/hed.26102. Epub 2020 Feb 12.
7
Effect of cervical manipulation on vertebral artery and cerebral haemodynamics in patients with chronic neck pain: a crossover randomised controlled trial.颈椎推拿对慢性颈痛患者椎动脉和脑血流动力学的影响:一项交叉随机对照试验。
BMJ Open. 2019 May 28;9(5):e025219. doi: 10.1136/bmjopen-2018-025219.
8
Accelerated Risk of Premature Ischemic Stroke in 5-Year Survivors of Nasopharyngeal Carcinoma.鼻咽癌 5 年幸存者缺血性中风的加速风险。
Oncologist. 2019 Sep;24(9):e891-e897. doi: 10.1634/theoncologist.2018-0747. Epub 2019 Mar 21.
9
Neck-tongue syndrome.颈-舌综合征
BMJ Case Rep. 2018 Dec 4;11(1):e227483. doi: 10.1136/bcr-2018-227483.
10
Pulsatile Tinnitus: Differential Diagnosis and Radiological Work-Up.搏动性耳鸣:鉴别诊断与影像学检查
Curr Radiol Rep. 2017;5(1):5. doi: 10.1007/s40134-017-0199-7. Epub 2017 Jan 24.