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了解儿童功能性腹痛障碍:多学科专家共识声明

Understanding functional abdominal pain disorders among children: a multidisciplinary expert consensus statement.

作者信息

Vandenplas Yvan, Darma Andy, Indrio Flavia, Aw Marion, Vieira Mario C, Vivatvakin Boosba, Treepongkaruna Suporn, Cruchet Sylvia, Acharyya Bhaswati C, Vázquez Rodrigo, Yeung Chun Yan, Gutiérrez Pedro

机构信息

Department of KidZ Health Castle, UZ Brussel, Vrije Universitiet Brussels, Brussels, Belgium.

Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.

出版信息

Front Pediatr. 2025 May 12;13:1576698. doi: 10.3389/fped.2025.1576698. eCollection 2025.

DOI:10.3389/fped.2025.1576698
PMID:40433476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12108103/
Abstract

INTRODUCTION

Functional abdominal pain disorders (FAPDs) are pediatric gastrointestinal conditions marked by chronic or recurrent abdominal pain without anatomical and/or biochemical abnormalities. This position paper guides primary care providers in the early diagnosis and management of FAPDs to improve the well-being of affected children and their families.

METHODS

A 12-member expert advisory board reviewed current approaches to diagnosing and managing FAPDs in children. Based on literature and discussions, 23 statements were drafted and voted on to achieve an acceptable level of agreement.

RESULTS

First-line healthcare professionals are key in diagnosing FAPDs, using ROME diagnostic criteria and recognizing red flags for accurate assessment and referrals. Comprehensive evaluation, including medical, dietary, and psychosocial history, physical exams, and basic tests helped to identify the initial triggers. Probiotics such as () DSM 17938 and () help in alleviating functional abdominal pain (FAP) in children along with primary measures, such as dietary modifications [a balanced diet advocating moderation in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP)-rich foods] and physical activity. Probiotics should be given for 6-8 weeks and can be resumed if symptoms recur. Cognitive-behavioral and hypnotic therapy also help, with remote options such as web-based, compact disk (CD)-based or application-based tools available.

DISCUSSION

This position paper provides expert insights to guide primary care providers in diagnosing and managing FAPDs, equipping them to make informed decisions for effective management of FAPDs.

摘要

引言

功能性腹痛障碍(FAPDs)是小儿胃肠道疾病,其特征为慢性或复发性腹痛,且无解剖学和/或生物化学异常。本立场文件指导初级保健提供者对FAPDs进行早期诊断和管理,以改善受影响儿童及其家庭的健康状况。

方法

一个由12名成员组成的专家咨询委员会审查了当前诊断和管理儿童FAPDs的方法。基于文献和讨论,起草了23项声明并进行表决,以达成可接受的共识水平。

结果

一线医疗保健专业人员在诊断FAPDs方面起着关键作用,他们使用罗马诊断标准并识别警示信号,以进行准确评估和转诊。全面评估,包括医疗、饮食和心理社会病史、体格检查和基本检查,有助于确定最初的触发因素。益生菌如()DSM 17938和()与主要措施(如饮食调整[倡导适度摄入富含可发酵低聚糖、双糖、单糖和多元醇(FODMAP)的食物的均衡饮食]和体育活动)一起,有助于缓解儿童的功能性腹痛(FAP)。益生菌应服用6 - 8周,如果症状复发可重新服用。认知行为疗法和催眠疗法也有帮助,还有基于网络、光盘(CD)或应用程序的远程治疗选项。

讨论

本立场文件提供了专家见解,以指导初级保健提供者诊断和管理FAPDs,使他们能够做出明智的决策,有效地管理FAPDs。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/758b/12108103/5ce9a610c988/fped-13-1576698-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/758b/12108103/c8247b4bdf0e/fped-13-1576698-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/758b/12108103/3e394d4e29fe/fped-13-1576698-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/758b/12108103/5ce9a610c988/fped-13-1576698-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/758b/12108103/c8247b4bdf0e/fped-13-1576698-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/758b/12108103/3e394d4e29fe/fped-13-1576698-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/758b/12108103/5ce9a610c988/fped-13-1576698-g003.jpg

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Functional abdominal pain disorders in children in southern Anhui Province, China are related to academic stress rather than academic performance.中国皖南地区儿童功能性腹痛与学业压力相关,而非学业表现。
BMC Pediatr. 2023 Jun 29;23(1):333. doi: 10.1186/s12887-023-04154-3.
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A Low-FODMAP Diet in the Management of Children With Functional Abdominal Pain Disorders: A Protocol of a Systematic Review.
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JPGN Rep. 2021 Mar 30;2(2):e065. doi: 10.1097/PG9.0000000000000065. eCollection 2021 May.
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Ability of polymicrobial probiotic and mono-strain probiotic to reduce functional abdominal pain in children: a randomized clinical trial.多菌株益生菌和单菌株益生菌减轻儿童功能性腹痛的能力:一项随机临床试验。
Clin Exp Pediatr. 2022 Dec;65(12):589-594. doi: 10.3345/cep.2022.00339. Epub 2022 Oct 31.
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Early life events in functional abdominal pain disorders in children.儿童功能性腹痛障碍的早期生活事件。
PLoS One. 2022 Nov 2;17(11):e0275419. doi: 10.1371/journal.pone.0275419. eCollection 2022.
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