Suppr超能文献

急性缺血性卒中(AIS)人群中非侵入性血红蛋白(nHgb)监测的准确性。

Accuracy of Non-Invasive Hemoglobin (nHgb) Monitoring in an AIS Population.

作者信息

McIntosh Amy L, McLeod Christopher

机构信息

Scottish Rite for Children, Dallas, TX.

出版信息

J Pediatr Soc North Am. 2024 Feb 12;5(2):598. doi: 10.55275/JPOSNA-2023-598. eCollection 2023 May.

Abstract

: Needle phobia and fear of blood draws are very common in children and adolescents. Noninvasive hemoglobin (nHgb) monitoring in children was first introduced in the Intensive Care Unit (ICU) setting. Later, our total joint arthroplasty colleagues demonstrated that nHgB monitoring was more efficient, less expensive, and preferred by patients compared to invasive hemoglobin (iHgb) monitoring. The goal of this Quality Initiative (QI) project is to compare the accuracy and reliability when comparing nHgb monitoring and iHgb (blood draw) in an Adolescent Idiopathic Scoliosis (AIS) population. The purpose was to evaluate the correlation between nHgb and iHgb monitoring and develop a nHgb threshold above which a patient would no longer require a blood draw, thus minimizing resource utilization as well as blood draw-related anxiety and pain during the postoperative period. We enrolled 60 consecutive patients undergoing posterior spine fusion/instrumentation (PSFI) for AIS. Average estimated blood loss (EBL) was 415cc, and 189 cc was returned via cell saver. 2/60 (3.3%) patients required an allogenic blood transfusion perioperatively. nHgb and iHgb values were obtained within 60 minutes of each other at three separate time points (preoperative, in Post-Anesthesia Care Unit (PACU), and postoperative day (POD 1) at 0700) iHgb and nHgb values were recorded. The results were retrospectively reviewed and analyzed. Paired t tests were utilized to compare mean (n/i) Hgb values. Pearson correlation coefficients were calculated at all three time points. Receiver Operating Characteristic (ROC) curve analysis was performed on the postoperative values to determine a threshold. There was a moderate positive correlation at all three time points (0.4, 0.59, 0.6) (p= 0.005, <0.001, <0.001). At all three time points, the mean nHgb value was 1-2 g/dL higher than the mean iHgb value, and this was statistically significant. Guidelines for an Allogenic Blood Transfusion (ABT) at our institution were developed through consensus between the surgical and anesthesia teams. Indications for a postoperative ABT include iHgb 7.0 - 8.0 g/dL along with clinical signs of anemia such as persistent hypotension, tachycardia, dyspnea, lethargy, confusion, postural dizziness not responsive to a fluid challenge, or iHgb <7.0 g/dL, regardless of signs/symptoms of anemia. There were not enough data points to correlate nHgb measurements with a patient's need to receive an ABT due to the low occurrence rate (3.3%). Therefore, we focused on a nHgb threshold at which a postoperative venous blood draw would not be necessary. 54/60 patients had a lab value of iHgb ≥ 9.0g/dL at 0700 on POD 1 and only 6 of the 60 patients had an iHgb ≤ 8.0 g/dL. Thus, we chose iHgb ≥ 9.0g/dL as the threshold. Based on data from the ROC curve analysis, a patient with a nHgb value of ≥10.8 g/dL had an iHgb value of ≥9.0 g/dL with 87% sensitivity. Based on the ABT guidelines stated above, no patient with a nHgb ≥ 10.8 g/dl would require an ABT, therefore a venipuncture would be unnecessary. Noninvasive Hgb monitoring was found to correlate with iHgb in pediatric AIS patients undergoing PSFI. Surgeons could consider screening AIS patients postoperatively with nHgb monitoring and only order iHgb measurement if the nHgb value is <10.8 g/dL resulting in improvement in the patient experience.

摘要

针头恐惧症和害怕采血在儿童和青少年中非常常见。儿童无创血红蛋白(nHgb)监测最初是在重症监护病房(ICU)环境中引入的。后来,我们全关节置换领域的同事表明,与有创血红蛋白(iHgb)监测相比,nHgB监测效率更高、成本更低,且更受患者青睐。 这个质量改进(QI)项目的目标是比较在青少年特发性脊柱侧凸(AIS)人群中nHgb监测和iHgb(采血)的准确性和可靠性。目的是评估nHgb和iHgb监测之间的相关性,并确定一个nHgb阈值,高于该阈值患者将不再需要采血,从而在术后期间最大限度地减少资源利用以及与采血相关的焦虑和疼痛。 我们连续招募了60例接受后路脊柱融合/内固定术(PSFI)治疗AIS的患者。平均估计失血量(EBL)为415cc,通过血液回收机回输了189cc。2/60(3.3%)的患者围手术期需要异体输血。在三个不同时间点(术前、麻醉后护理单元(PACU)和术后第1天07:00),在彼此60分钟内获取nHgb和iHgb值并记录。对结果进行回顾性审查和分析。采用配对t检验比较平均(n/i)Hgb值。在所有三个时间点计算Pearson相关系数。对术后值进行受试者操作特征(ROC)曲线分析以确定阈值。 在所有三个时间点均存在中度正相关(0.4、0.59、0.6)(p = 0.005、<0.001、<0.001)。在所有三个时间点,平均nHgb值比平均iHgb值高1 - 2g/dL,且具有统计学意义。我们机构的异体输血(ABT)指南是通过外科和麻醉团队之间的共识制定的。术后ABT的指征包括iHgb 7.0 - 8.0g/dL以及贫血的临床体征,如持续低血压、心动过速、呼吸困难、嗜睡、意识模糊、对液体冲击无反应的体位性头晕,或iHgb <7.0g/dL,无论有无贫血的体征/症状。由于发生率较低(3.3%),没有足够的数据点将nHgb测量值与患者接受ABT的需求相关联。因此,我们专注于确定一个术后无需静脉采血的nHgb阈值。60例患者中有54例在术后第1天07:00时iHgb值≥9.0g/dL,60例患者中只有6例iHgb≤8.0g/dL。因此,我们选择iHgb≥9.0g/dL作为阈值。根据ROC曲线分析数据,nHgb值≥10.8g/dL的患者iHgb值≥9.0g/dL的敏感性为87%。根据上述ABT指南,nHgb≥10.8g/dl的患者无需ABT,因此无需静脉穿刺。 研究发现,在接受PSFI的儿科AIS患者中,无创Hgb监测与iHgb相关。外科医生可以考虑在术后用nHgb监测筛查AIS患者,仅在nHgb值<10.8g/dL时才进行iHgb测量,从而改善患者体验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fde/12088093/bba59ec47590/gr1.jpg

相似文献

1
Accuracy of Non-Invasive Hemoglobin (nHgb) Monitoring in an AIS Population.
J Pediatr Soc North Am. 2024 Feb 12;5(2):598. doi: 10.55275/JPOSNA-2023-598. eCollection 2023 May.
3
Noninvasive Hemoglobin Monitoring for Postoperative Pediatric Orthopaedic Patients: A Preliminary Study.
J Pediatr Orthop. 2022 Sep 1;42(8):e897-e900. doi: 10.1097/BPO.0000000000002199. Epub 2022 Jul 13.
4
Prospective Noninvasive Hemoglobin Monitoring in the Outpatient Total Joint Arthroplasty Setting.
J Bone Joint Surg Am. 2025 Feb 19;107(4):364-371. doi: 10.2106/JBJS.24.00438. Epub 2024 Dec 20.
6
[Standard technical specifications for methacholine chloride (Methacholine) bronchial challenge test (2023)].
Zhonghua Jie He He Hu Xi Za Zhi. 2024 Feb 12;47(2):101-119. doi: 10.3760/cma.j.cn112147-20231019-00247.
7
The pattern of blood loss in adolescent idiopathic scoliosis.
Spine J. 2014 Dec 1;14(12):2938-45. doi: 10.1016/j.spinee.2014.05.022. Epub 2014 Jun 7.
9
Hidden blood loss in adolescent idiopathic scoliosis surgery.
Orthop Traumatol Surg Res. 2022 Oct;108(6):103216. doi: 10.1016/j.otsr.2022.103216. Epub 2022 Jan 31.
10
The incidence and risk factors for perioperative allogeneic blood transfusion in primary idiopathic scoliosis surgery.
Spine Deform. 2020 Aug;8(4):695-702. doi: 10.1007/s43390-020-00093-6. Epub 2020 Mar 9.

本文引用的文献

1
Fear of Injections and Needle Phobia Among Children and Adolescents: An Overview of Psychological, Behavioral, and Contextual Factors.
SAGE Open Nurs. 2018 Mar 14;4:2377960818759442. doi: 10.1177/2377960818759442. eCollection 2018 Jan-Dec.
2
Evaluation of noninvasive hemoglobin monitoring in children with congenital heart diseases.
Paediatr Anaesth. 2020 May;30(5):571-576. doi: 10.1111/pan.13851. Epub 2020 Mar 25.
3
The incidence and risk factors for perioperative allogeneic blood transfusion in primary idiopathic scoliosis surgery.
Spine Deform. 2020 Aug;8(4):695-702. doi: 10.1007/s43390-020-00093-6. Epub 2020 Mar 9.
4
High Satisfaction in Adolescent Idiopathic Scoliosis Patients on Enhanced Discharge Pathway.
J Pediatr Orthop. 2020 Mar;40(3):e166-e170. doi: 10.1097/BPO.0000000000001436.
9
Trending and accuracy of noninvasive hemoglobin monitoring in pediatric perioperative patients.
Anesth Analg. 2014 Oct;119(4):920-925. doi: 10.1213/ANE.0000000000000369.
10
The accuracy of noninvasive hemoglobin monitoring using the radical-7 pulse CO-Oximeter in children undergoing neurosurgery.
Anesth Analg. 2012 Dec;115(6):1302-7. doi: 10.1213/ANE.0b013e31826b7e38. Epub 2012 Nov 9.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验