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Ovulation triggers oxytocin gene expression in the bovine ovary.

作者信息

Ivell R, Brackett K H, Fields M J, Richter D

出版信息

FEBS Lett. 1985 Oct 14;190(2):263-7. doi: 10.1016/0014-5793(85)81296-5.

DOI:10.1016/0014-5793(85)81296-5
PMID:4043404
Abstract

The gene for the nonapeptide neurohormone oxytocin is highly expressed in the bovine corpus luteum. Measurements of oxytocin-specific mRNA through the oestrous cycle of non-pregnant cows show that transcription is maximal accompanying ovulation and decreases rapidly thereafter. In contrast, immunohistochemistry shows neurophysin peptide levels to be greatest at mid-cycle. Low levels of oxytocin mRNA are detected in follicles and in the luteolytic half of the cycle. This mRNA is virtually absent in the corpus luteum of pregnant cattle. No cyclicity is evident in hypothalamic oxytocin mRNA levels.

摘要

相似文献

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J Clin Invest. 1993 Jan;91(1):185-92. doi: 10.1172/JCI116169.
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Two orphan receptors binding to a common site are involved in the regulation of the oxytocin gene in the bovine ovary.两种结合到共同位点的孤儿受体参与了牛卵巢中催产素基因的调控。
Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1440-4. doi: 10.1073/pnas.91.4.1440.
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Nucleotide sequence of a full length cDNA clone encoding the oxytocin-neurophysin I precursor isolated from the ovine corpus luteum.从绵羊黄体中分离出的编码催产素-神经垂体素I前体的全长cDNA克隆的核苷酸序列。
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