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静脉畸形术前胶水栓塞的手术室使用情况分析:手术时间及结果

Room utilization analysis of pre-operative glue embolization for venous malformations: procedure times and outcomes.

作者信息

Reis Joseph, Wang Xing, Perkins Jonathan, Lindberg Antoinette, Roberts Jesse, Iyer Ramesh, Bogart Aaron, Shivaram Giri

机构信息

Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, 98105, USA.

出版信息

Pediatr Radiol. 2025 May 28. doi: 10.1007/s00247-025-06270-x.

Abstract

BACKGROUND

Pre-operative n-butyl-2-cyanoacrylate embolization and surgical resection is an established treatment for venous malformations. A single-session treatment is optimal but requires accurate procedural time estimates for the interventional radiology and surgical portions of the treatment to optimize coordination. Understanding the variables affecting room time could improve coordination, raise efficiency, and eventually help to estimate cost for patients.

OBJECTIVE

Identify which factors have a significant impact on the room time for pre-operative glue embolization of venous malformations.

MATERIALS AND METHODS

A single institution, institutional review board-approved, retrospective study of glue embolization procedures was performed over an 8-year period. The impacts of patient, operator, technical factors, and malformation characteristics on procedure time and room time were analyzed using univariate and multivariate log-transformed linear mixed models to account for data skewedness.

RESULTS

A total of 232 patients were identified with a median age of 13 years (IQR, 8.5; 16 years) and median weight of 48 kg (IQR, 27; 64 kg). Higher Puig's classification number (β range, -0.04-0.41; P=0.02), larger malformation dimension (β=0.0031; P<0.001), use of cone beam CT (β=0.29; P<0.001), and the presence of adverse events (β=0.54; P<0.001) significantly increased procedure time on multivariate analysis. The presence of an adverse event (β=0.3100; P<0.001), use of cone beam CT utilization (β=0.1600; P<0.001), and larger venous malformation dimension (β=0.0017; P<0.001) significantly lengthened total room time. The performing physician additionally impacted both total room times (P<0.001); however, the experience level with glue embolization varied significantly between providers (P<0.001) and was felt to be a contributing factor.

CONCLUSION

The room time required for n-butyl-2-cyanoacrylate embolization prior to venous malformation resection is significantly dependent on the presence of complications, cone beam CT use, malformation size, and performing physician experience.

摘要

背景

术前使用正丁基-2-氰基丙烯酸酯栓塞并结合手术切除是治疗静脉畸形的既定方法。单次治疗是最佳选择,但需要对治疗过程中介入放射学和手术部分的操作时间进行准确估计,以优化协调。了解影响手术室时间的变量可以改善协调、提高效率,并最终有助于估算患者的费用。

目的

确定哪些因素对静脉畸形术前胶水栓塞的手术室时间有显著影响。

材料与方法

在一个单一机构进行了一项经机构审查委员会批准的回顾性研究,研究胶水栓塞手术,为期8年。使用单变量和多变量对数转换线性混合模型分析患者、操作者、技术因素和畸形特征对手术时间和手术室时间的影响,以处理数据的偏态性。

结果

共纳入232例患者,中位年龄为13岁(四分位间距,8.5;16岁),中位体重为48kg(四分位间距,27;64kg)。在多变量分析中,较高的普伊格分类数(β范围,-0.04 - 0.41;P = 0.02)、较大的畸形尺寸(β = 0.0031;P < 0.001)、使用锥形束CT(β = 0.29;P < 0.001)以及出现不良事件(β = 0.54;P < 0.001)均显著增加手术时间。出现不良事件(β = 0.3100;P < 0.001)、使用锥形束CT(β = 0.1600;P < 0.001)以及较大的静脉畸形尺寸(β = 0.0017;P < 0.001)均显著延长总手术室时间。执行医生也对总手术室时间有影响(P < 0.001);然而,不同医生之间胶水栓塞的经验水平差异显著(P < 0.001),这被认为是一个影响因素。

结论

静脉畸形切除术前正丁基-2-氰基丙烯酸酯栓塞所需的手术室时间显著取决于并发症的出现、锥形束CT的使用、畸形大小以及执行医生的经验。

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