Bayne C J, Boswell C A, Loker E S, Yui M A
Dev Comp Immunol. 1985 Summer;9(3):523-30. doi: 10.1016/0145-305x(85)90015-1.
Blood plasmas from certain strains of Biomphalaria glabrata are known to have components which facilitate a hemocyte-effected cytotoxic response against encapsulated Schistosoma mansoni sporocysts. The possible identity of the factor(s) has been investigated. Sporocysts placed in snail plasma rapidly acquire a wide variety of host plasma antigens, at least some of which are displayed on the parasite surface. Plasmas from strains of snail resistant to the parasite agglutinate fixed sporocysts, while plasmas from susceptible strains fail to do so. Fixed sporocysts incubated in plasma bind selectively a subpopulation of plasma antigens; some are bound uniquely in resistant plasma. Another resembles a hemagglutinin from snail plasma. These and other recently acquired data are discussed in light of increasing evidence for defensive roles of multivalent lectins.
已知来自某些光滑双脐螺菌株的血浆含有一些成分，这些成分有助于血细胞对被包囊的曼氏血吸虫子孢蚴产生细胞毒性反应。已经对这些因子的可能身份进行了研究。置于蜗牛血浆中的子孢蚴会迅速获得多种宿主血浆抗原，其中至少有一些会显示在寄生虫表面。来自对该寄生虫具有抗性的蜗牛菌株的血浆会凝集固定的子孢蚴，而来自易感菌株的血浆则不会。在血浆中孵育的固定子孢蚴会选择性结合血浆抗原的一个亚群；有些抗原仅在抗性血浆中结合。另一种类似于来自蜗牛血浆的血凝素。鉴于越来越多的证据表明多价凝集素具有防御作用，本文对这些以及其他最近获得的数据进行了讨论。
