糖尿病和吸烟与慢性肾病患者的少肌性腹型肥胖相关：一项横断面研究。
Diabetes and smoking are associated with dynapenic abdominal obesity in patients with chronic kidney disease: a cross-sectional study.
作者信息
Almeida-Menezes Alessandra Fortes, Conceição-Machado Maria Ester Pereira da, Gusmão Maria Helena Lima, Ramos Lílian Barbosa, Nascimento Thais Vitorino Neves do, Amaral Magali Teresópolis Reis, Barreto-Medeiros Jairza Maria
机构信息
Postgraduate Program in Food, Nutrition and Health, School of Nutrition, Universidade Federal da Bahia (UFBA), Salvador (BA), Brazil.
Department of Statistics, Universidade Estadual de Feira de Santana (UEFS), Feira de Santana (BA), Brazil.
出版信息
Sao Paulo Med J. 2025 May 26;143(3):e2023232. doi: 10.1590/1516-3180.2023.0232.R2.21102024. eCollection 2025.
BACKGROUND
No study has reported about the prevalence and factors associated with dynapenic abdominal obesity in patients with pre-dialysis chronic kidney disease (CKD).
OBJECTIVE
Evaluation of the prevalence of dynapenic abdominal obesity and its relationship with sociodemographic, lifestyle, clinical, and nutritional variables in patients with CKD not dependent on dialysis.
DESIGN AND SETTING
A cross-sectional study was conducted at the Nutrition and Nephropathy Outpatient Clinic (public service) in Bahia, Brazil.
METHODS
This cross-sectional study was conducted on 102 patients of both sexes, aged ≥ 20 years. Dynapenic abdominal obesity (DAO) was defined as the simultaneous presence of dynapenia (handgrip strength less than the first tertile of the sample itself, according to sex and age) and increased waist circumference. Differences between groups with and without DAO were assessed using the Student's Mann-Whitney t-test, Pearson's chi-square test, or Fisher's exact test. Associations were tested using bivariate and multivariate models with Poisson regression to calculate the prevalence ratio and 95% confidence intervals (PR; 95% CI).
RESULTS
The mean age of the patients was 58.7 (standard deviation = 11.69); 50.5% were male, 51.6% were elderly, 41.8% had diabetes, 5.5% were smokers, 58.2% were abdominally obese, and 38.5% were dynapenic. DAO was identified in 18.7% of participants and was associated with diabetes mellitus (PR = 2.8; 95% CI = 1.12-6.99) and smoking (PR = 3.22; 95% CI = 1.16-8.96).
CONCLUSION
Non-dialysis dependent patients with CKD showed a significant prevalence of DAO associated with smoking and diabetes mellitus.
背景
尚无研究报道透析前慢性肾脏病（CKD）患者中肌无力性腹型肥胖的患病率及相关因素。
目的
评估非透析依赖的CKD患者中肌无力性腹型肥胖的患病率及其与社会人口学、生活方式、临床和营养变量的关系。
设计与地点
在巴西巴伊亚州的营养与肾病门诊（公共服务机构）进行了一项横断面研究。
方法
该横断面研究纳入了102名年龄≥20岁的男女患者。肌无力性腹型肥胖（DAO）定义为同时存在肌无力（根据性别和年龄，握力低于样本自身的第一个三分位数）和腰围增加。采用Student's Mann-Whitney t检验、Pearson卡方检验或Fisher精确检验评估有无DAO组之间的差异。使用双变量和多变量模型以及Poisson回归进行关联检验，以计算患病率比和95%置信区间（PR；95%CI）。
结果
患者的平均年龄为58.7岁（标准差=11.69）；50.5%为男性，51.6%为老年人，41.8%患有糖尿病，5.5%为吸烟者，58.2%为腹型肥胖，38.5%存在肌无力。18.7%的参与者被诊断为DAO，且与糖尿病（PR=2.8；95%CI=1.12-6.99）和吸烟（PR=3.22；95%CI=1.16-8.96）相关。
结论
非透析依赖的CKD患者中DAO的患病率较高，且与吸烟和糖尿病相关。
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