Molina-Rios Sebastian, Galindo Leonardo, Calderón Diana Gil, Yate Jose, Rubio Manuela, Cajas-Santana Luis Javier
Department of Internal Medicine, Rheumatology Unit, Universidad Nacional de Colombia, Bogotá, Colombia.
Department of Internal Medicine, Rheumatology Unit, Hospital Universitario Nacional de Colombia, Bogotá, Colombia.
Clin Rheumatol. 2025 May 29. doi: 10.1007/s10067-025-07475-z.
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of inflammatory conditions that can potentially affect multiple systems, with respiratory involvement being a common manifestation. Pulmonary emphysema as a sole manifestation is extremely rare. We report a case series of three patients diagnosed with AAV as a potential cause of pulmonary emphysema. Additionally, we conducted a systematic review of the literature to explore this association.
抗中性粒细胞胞浆抗体（ANCA）相关性血管炎（AAV）是一组可能影响多个系统的炎症性疾病，呼吸系统受累是常见表现。仅以肺气肿为唯一表现极为罕见。我们报告了一系列三例被诊断为AAV且可能是肺气肿病因的病例。此外，我们对文献进行了系统回顾以探讨这种关联。
