Mori Takeshi, Aoyama Hidekazu, Tanaka Akimitsu, Kato Kazuo
Department of Cardiology, Nagoya Tokushukai General Hospital, Kasugai, Aichi, Japan.
Department of Cardiology, Ama Municipal Hospital, Aichi, Japan.
Catheter Cardiovasc Interv. 2025 Aug;106(2):943-948. doi: 10.1002/ccd.31639. Epub 2025 May 28.
Spontaneous coronary artery dissection (SCAD) is a rare but critical cause of acute myocardial infarction (AMI). Diagnosing SCAD solely based on angiographic findings is often challenging; therefore, intravascular imaging modalities such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are often required. Angioscopy allows for direct visualization of the vascular lumen, enabling detailed assessment. Herein, we present a unique case of a young man who presented with AMI. Coronary angiography (CAG) revealed diffuse stenosis in the first septal branch; therefore, IVUS, OCT, and angioscopy were performed to obtain images with unprecedented details to evaluate the dissected cavity. Consequently, SCAD was confirmed owing to the identification of a dissected false lumen and a medial layer disruption. Mild atherosclerotic lesions were observed on coronary angioscopy. SCAD has traditionally been considered unrelated to atherosclerosis; however, our findings may indicate a potential pathophysiological link. This comprehensive imaging approach highlights the potential to improve the understanding of SCAD. This is the first case in which the dissection entry of SCAD was observed in detail using angiography.
自发性冠状动脉夹层(SCAD)是急性心肌梗死(AMI)的一种罕见但严重的病因。仅基于血管造影结果诊断SCAD往往具有挑战性;因此,通常需要血管内超声(IVUS)和光学相干断层扫描(OCT)等血管内成像方式。血管内镜可直接观察血管腔,从而进行详细评估。在此,我们报告一例年轻男性急性心肌梗死的独特病例。冠状动脉造影(CAG)显示第一间隔支弥漫性狭窄;因此,进行了IVUS、OCT和血管内镜检查,以获取具有前所未有的细节的图像,以评估夹层腔。结果,由于发现了夹层假腔和中层破坏,确诊为SCAD。在冠状动脉血管内镜检查中观察到轻度动脉粥样硬化病变。传统上认为SCAD与动脉粥样硬化无关;然而,我们的发现可能表明存在潜在的病理生理联系。这种综合成像方法凸显了增进对SCAD理解的潜力。这是首例使用血管造影详细观察到SCAD夹层入口的病例。