Cherkaoui Soukaina, Allalat Idriss, Lazraq Mariam, Zarzur Jamila, Cherti Mohamed
Cardiology, Ibn Sina University Hospital, Mohammed V University, Rabat, MAR.
Cardiology B, Ibn Sina University Hospital Center, Mohammed V University, Rabat, MAR.
Cureus. 2025 Jul 16;17(7):e88099. doi: 10.7759/cureus.88099. eCollection 2025 Jul.
Spontaneous coronary artery dissection (SCAD) is a rare and underrecognized cause of acute coronary syndrome (ACS), particularly in young and middle-aged women without traditional cardiovascular risk factors. While most cases heal spontaneously, a subset may persist, evolving into what can be considered a chronic coronary artery dissection (CCAD). This chronic form remains poorly defined and rarely documented. A 44-year-old woman with a history of ST-elevation myocardial infarction (STEMI) presented several months later with recurrent chest pain. Coronary angiography revealed a persistent dissection in the mid-left anterior descending (LAD) artery without signs of active ischemia or evolving intramural hematoma. No advanced imaging was performed, but the stability of angiographic findings over time and the absence of ischemic symptoms supported the diagnosis of a chronic dissection. The initial STEMI was retrospectively considered to have resulted from an unrecognized SCAD. Given the lack of ischemia and the risks associated with intervention in SCAD, conservative management was continued. The patient remained asymptomatic and free of major cardiac events over a 12-month follow-up period. Chronic dissection may be overlooked in patients with a history of SCAD. Although angiography remains the main diagnostic tool, it has limitations, and adjunctive imaging such as intravascular ultrasound (IVUS), optical coherence tomography (OCT), or coronary computed tomography angiography (CCTA) may help confirm chronicity. Current understanding of the long-term course of SCAD, including recurrence risk and follow-up strategies, is still limited. CCAD should be considered in patients with recurrent chest pain and prior SCAD history. Further studies are needed to better define its prognosis, recurrence risk, and optimal monitoring strategies.
自发性冠状动脉夹层(SCAD)是急性冠状动脉综合征(ACS)的一种罕见且未被充分认识的病因,在无传统心血管危险因素的中青年女性中尤为常见。虽然大多数病例可自发愈合,但有一部分可能持续存在,发展为可被视为慢性冠状动脉夹层(CCAD)的情况。这种慢性形式的定义仍不明确,且鲜有记录。一名有ST段抬高型心肌梗死(STEMI)病史的44岁女性在数月后出现复发性胸痛。冠状动脉造影显示左前降支(LAD)中段存在持续性夹层,无活动性缺血或进展性壁内血肿的迹象。未进行高级成像检查,但造影结果随时间的稳定性以及无缺血症状支持慢性夹层的诊断。最初的STEMI经回顾性分析被认为是由未被识别的SCAD所致。鉴于缺乏缺血情况以及SCAD干预相关的风险,继续采取保守治疗。在12个月的随访期内,患者无症状且未发生重大心脏事件。有SCAD病史的患者可能会忽视慢性夹层。尽管血管造影仍是主要的诊断工具,但它有局限性,血管内超声(IVUS)、光学相干断层扫描(OCT)或冠状动脉计算机断层扫描血管造影(CCTA)等辅助成像可能有助于确认慢性情况。目前对SCAD长期病程的了解,包括复发风险和随访策略,仍然有限。有复发性胸痛和既往SCAD病史的患者应考虑CCAD。需要进一步研究以更好地明确其预后、复发风险和最佳监测策略。