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水生共生基因组计划:探索生命之树中共生关系的进化

The Aquatic Symbiosis Genomics Project: probing the evolution of symbiosis across the Tree of Life.

作者信息

McKenna Victoria, Archibald John M, Beinart Roxanne, Dawson Michael N, Hentschel Ute, Keeling Patrick J, Lopez Jose V, Martín-Durán José M, Petersen Jillian M, Sigwart Julia D, Simakov Oleg, Sutherland Kelly R, Sweet Michael, Talbot Nicholas J, Thompson Anne W, Bender Sara, Harrison Peter W, Rajan Jeena, Cochrane Guy, Berriman Matthew, Lawniczak Mara K N, Blaxter Mark

机构信息

Tree of Life, Wellcome Sanger Institute, Cambridge, CB10 1SA, UK.

Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia, B3H 4R2, Canada.

出版信息

Wellcome Open Res. 2024 Jun 10;6:254. doi: 10.12688/wellcomeopenres.17222.2. eCollection 2021.

Abstract

We present the Aquatic Symbiosis Genomics Project, a global collaboration to generate high quality genome sequences for a wide range of eukaryotes and their microbial symbionts. Launched under the Symbiosis in Aquatic Systems Initiative of the Gordon and Betty Moore Foundation, the ASG Project brings together researchers from across the globe who hope to use these reference genomes to augment and extend their analyses of the dynamics, mechanisms and environmental importance of symbioses. Applying large-scale, high-throughput sequencing and assembly technologies, the ASG collaboration will assemble and annotate the genomes of 500 symbiotic organisms - both the "hosts" and the microbial symbionts with which they associate. These data will be released openly to benefit all who work on symbioses, from conservation geneticists to those interested in the origin of the eukaryotic cell.

摘要

我们推出了水生共生基因组计划,这是一项全球合作项目,旨在为广泛的真核生物及其微生物共生体生成高质量的基因组序列。该计划在戈登与贝蒂·摩尔基金会的水生系统共生倡议下启动,汇聚了全球各地的研究人员,他们希望利用这些参考基因组来加强和扩展对共生关系的动态、机制及环境重要性的分析。通过应用大规模、高通量测序和组装技术,水生共生基因组计划合作团队将组装和注释500种共生生物的基因组——包括“宿主”及其相关的微生物共生体。这些数据将公开发布,以使所有从事共生关系研究的人员受益,从保护遗传学家到对真核细胞起源感兴趣的人员。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c01d/12117324/f648fdfafe2e/wellcomeopenres-6-24685-g0000.jpg

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