乳糜泻与 Dupuytren 挛缩症的发病：一项全国范围的匹配队列分析。
Celiac Disease and Incident Dupuytren's Contracture: A Matched Nationwide Cohort Analysis.
作者信息
Yuan Shuai, Furniss Dominic, Larsson Susanna C, Leffler Daniel A, Ludvigsson Jonas F
机构信息
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
出版信息
Clin Epidemiol. 2025 May 24;17:481-484. doi: 10.2147/CLEP.S518939. eCollection 2025.
Abstract
This study explored the association between celiac disease (CeD) and Dupuytren's contracture (DC) using data from the Swedish ESPRESSO cohort. We analyzed 49,699 CeD patients and 245,267 matched controls, identifying 1420 incident DC cases. CeD patients had a 1.21-fold increased risk of DC compared to controls, with a more pronounced risk in women and older individuals. Further research is needed to understand the underlying mechanisms of this relationship.
摘要
本研究利用瑞典ESPRESSO队列的数据，探讨了乳糜泻（CeD）与杜普伊特伦挛缩症（DC）之间的关联。我们分析了49699例CeD患者和245267例匹配的对照，确定了1420例新发DC病例。与对照组相比，CeD患者发生DC的风险增加了1.21倍，女性和老年人的风险更为明显。需要进一步研究以了解这种关系的潜在机制。
相似文献
1
Celiac Disease and Incident Dupuytren's Contracture: A Matched Nationwide Cohort Analysis.乳糜泻与 Dupuytren 挛缩症的发病：一项全国范围的匹配队列分析。
Clin Epidemiol. 2025 May 24;17:481-484. doi: 10.2147/CLEP.S518939. eCollection 2025.
2
Collagenase injection versus limited fasciectomy surgery to treat Dupuytren's contracture in adult patients in the UK: DISC, a non-inferiority RCT and economic evaluation.英国成年患者中胶原酶注射与有限筋膜切除术治疗掌腱膜挛缩症的比较：DISC，一项非劣效性随机对照试验及经济学评估
Health Technol Assess. 2024 Dec;28(78):1-262. doi: 10.3310/KGXD8528.
3
Therapy for Dupuytren's Disease: Collagenase Therapy-A Long-Term Follow-Up Study.掌腱膜挛缩症的治疗：胶原酶治疗——一项长期随访研究。
Life (Basel). 2024 Oct 8;14(10):1275. doi: 10.3390/life14101275.
4
Association between Stenosing Tenosynovitis and Dupuytren's Contracture in the Hand.手部狭窄性腱鞘炎与掌腱膜挛缩症之间的关联
Plast Reconstr Surg Glob Open. 2019 Jan 11;7(1):e2088. doi: 10.1097/GOX.0000000000002088. eCollection 2019 Jan.
5
Cancer incidence in patients treated surgically for Dupuytren's contracture.接受手术治疗的掌腱膜挛缩症患者的癌症发病率。
J Hand Surg Br. 2000 Jun;25(3):283-7. doi: 10.1054/jhsb.2000.0382.
6
Dupuytren's Contracture: Incidence of Injury-Induced Cases and Specific Clinical Expression.杜普伊特伦挛缩：损伤诱导病例的发生率和特定临床表现。
Medicina (Kaunas). 2020 Jun 30;56(7):323. doi: 10.3390/medicina56070323.
7
A retrospective review of the management of Dupuytren's nodules.一项关于掌腱膜结节治疗的回顾性研究。
J Hand Surg Am. 2005 Sep;30(5):1014-8. doi: 10.1016/j.jhsa.2005.03.005.
8
Dupuytren's contracture: a retrospective database analysis to determine hospitalizations in the Netherlands.掌腱膜挛缩症：一项用于确定荷兰住院情况的回顾性数据库分析。
BMC Res Notes. 2011 Oct 12;4:402. doi: 10.1186/1756-0500-4-402.
9
Association of Morbus Ledderhose with Dupuytren's contracture.莱德尔霍斯病与杜普伊特伦挛缩的关联。
Foot Ankle Int. 2013 Jun;34(6):841-5. doi: 10.1177/1071100713475352. Epub 2013 Feb 5.
10
A study of the repeatability of the diagnosis of Dupuytren's contracture and its prevalence in the grampian region.一项关于杜普伊特伦挛缩症诊断重复性及其在格兰扁地区患病率的研究。
J Hand Surg Br. 1993 Apr;18(2):258-61. doi: 10.1016/0266-7681(93)90124-x.
本文引用的文献
1
Coeliac disease: complications and comorbidities.乳糜泻：并发症与合并症
Nat Rev Gastroenterol Hepatol. 2025 Apr;22(4):252-264. doi: 10.1038/s41575-024-01032-w. Epub 2025 Jan 28.
2
New Insights on Genes, Gluten, and Immunopathogenesis of Celiac Disease.新见解：乳糜泻的基因、 gluten 和免疫发病机制。
Gastroenterology. 2024 Jun;167(1):4-22. doi: 10.1053/j.gastro.2024.03.042. Epub 2024 Apr 24.
3
Celiac Disease-Related Conditions: Who to Test?乳糜泻相关疾病：应检测哪些人群？
Gastroenterology. 2024 Jun;167(1):64-78. doi: 10.1053/j.gastro.2024.02.044. Epub 2024 Mar 7.
4
Phenome-wide Mendelian randomization analysis reveals multiple health comorbidities of coeliac disease.表型全基因组 Mendelian 随机分析揭示乳糜泻的多种健康共病。
EBioMedicine. 2024 Mar;101:105033. doi: 10.1016/j.ebiom.2024.105033. Epub 2024 Feb 21.
5
Modifiable Risk Factors for Prevention in Dupuytren Disease: A UK Biobank Case-Control Study.可改变的掌腱膜挛缩症预防风险因素：英国生物库病例对照研究。
Plast Reconstr Surg. 2024 Feb 1;153(2):363e-372e. doi: 10.1097/PRS.0000000000010774. Epub 2023 May 31.
6
Dupuytren Disease: Prevalence, Incidence, and Lifetime Risk of Surgical Intervention. A Population-Based Cohort Analysis.掌腱膜挛缩症：手术干预的患病率、发病率和终生风险。一项基于人群的队列分析。
Plast Reconstr Surg. 2023 Mar 1;151(3):581-591. doi: 10.1097/PRS.0000000000009919. Epub 2022 Nov 22.
7
Anti-tumour necrosis factor therapy for early-stage Dupuytren's disease (RIDD): a phase 2b, randomised, double-blind, placebo-controlled trial.抗肿瘤坏死因子疗法治疗早期杜普伊特伦挛缩病（RIDD）：一项2b期随机双盲安慰剂对照试验
Lancet Rheumatol. 2022 Jun;4(6):E407-E416. doi: 10.1016/S2665-9913(22)00093-5. Epub 2022 Apr 29.
8
The worldwide prevalence of the Dupuytren disease: a comprehensive systematic review and meta-analysis.全球范围内的杜普伊特伦挛缩症患病率：一项全面的系统评价和荟萃分析。
J Orthop Surg Res. 2020 Oct 28;15(1):495. doi: 10.1186/s13018-020-01999-7.
9
Association Between Celiac Disease and Mortality Risk in a Swedish Population.乳糜泻与瑞典人群死亡风险的相关性。
JAMA. 2020 Apr 7;323(13):1277-1285. doi: 10.1001/jama.2020.1943.
10
Cohort profile: ESPRESSO (Epidemiology Strengthened by histoPathology Reports in Sweden).队列简介：ESPRESSO（瑞典组织病理学报告强化的流行病学研究）。
Clin Epidemiol. 2019 Jan 14;11:101-114. doi: 10.2147/CLEP.S191914. eCollection 2019.
Zotero 插件