Fuentes V, Lefebvre J F, Lema F, Bissac E, Orfila J
Immunol Lett. 1985;10(6):325-7. doi: 10.1016/0165-2478(85)90126-9.
Eleven stable anti-Chlamydia hybrid clones by fusions between X63-Ag8653 myelomas and immune splenocytes from Chlamydia psittaci immunized F1 (C57BL6 X BALB/c) mice have been established which react with the 12 reference Chlamydia strains (seven C. trachomatis and five C. psittaci. Ten of these monoclonal antibodies are directed against the genera-specific epitope (40,000 MW component) for which prolonged immunization seems to be responsible.
通过X63-Ag8653骨髓瘤细胞与来自鹦鹉热衣原体免疫的F1(C57BL6×BALB/c)小鼠的免疫脾细胞融合,已建立了11个稳定的抗衣原体杂交克隆,它们可与12种衣原体参考菌株(7种沙眼衣原体和5种鹦鹉热衣原体)发生反应。其中10种单克隆抗体针对属特异性表位(40,000 MW成分),似乎是长期免疫所致。