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走向更环保的处方?瑞典全科医生对减少药物污染政策的支持。

Towards greener prescribing? Swedish general practitioners' support for policies to reduce pharmaceutical pollution.

作者信息

Villén Johanna, Laux Johanna, Wettermark Björn, Sporrong Sofia Kälvemark, Nekoro Marmar, Håkonsen Helle

机构信息

Department of Pharmacy, Faculty of Pharmacy, Uppsala University, Uppsala, Sweden.

Department of Clinical Pharmacy, Institute of Pharmacy, Medical Faculty, Leipzig University, Leipzig, Germany.

出版信息

Br J Clin Pharmacol. 2025 Jun;91(6):1623-1631. doi: 10.1111/bcp.70066.

Abstract

AIMS

Prescribing pharmaceuticals is essential to improve health, but it also has substantial environmental impact. This study investigated the extent to which Swedish general practitioners (GPs) are willing to integrate environmental aspects into treatment decisions and their opinions on policies to reduce pharmaceutical pollution.

METHODS

A questionnaire assessing environmental considerations in prescribing was developed and distributed to 1233 Swedish GPs and physicians in training (response rate: 22%) between September 2023 and June 2024. It included 3 patient cases to assess trade-offs between therapeutic effect and environmental impact of pharmaceuticals used for pain management, blood pressure reduction, and contraception. Questions about attitudes to policies to reduce the environmental impact of pharmaceuticals were also included. Data were analysed using descriptive and inferential statistics.

RESULTS

Most respondents were willing to prescribe a less effective pharmaceutical if it was environmentally preferable, 77% for pain management and blood pressure reduction, and 50% for contraception. Environmental impact was ranked as the least important factor in prescribing decisions when compared to cost, regional treatment guidelines, dosage intervals, and user-friendliness. A total of 68% of respondents agreed that physicians should consider environmental aspects when prescribing, however only a few often searched for environmental information when prescribing. Policies directed towards other stakeholders, such as authorities and the pharmaceutical industry, received substantial support.

CONCLUSION

Swedish GPs are willing to consider environmental factors when prescribing. However, other factors are more often considered and GPs attribute higher responsibility to other actors. Improving access to environmental information about pharmaceuticals could support greener prescribing.

摘要

目的

开处方用药对于改善健康状况至关重要,但同时也会对环境产生重大影响。本研究调查了瑞典全科医生(GP)在多大程度上愿意将环境因素纳入治疗决策,以及他们对减少药物污染政策的看法。

方法

2023年9月至2024年6月期间,编制了一份评估开处方时环境考量因素的问卷,并分发给1233名瑞典全科医生和接受培训的医生(回复率:22%)。问卷包含3个患者病例,以评估用于疼痛管理、降压和避孕的药物在治疗效果和环境影响之间的权衡。还包括有关对减少药物环境影响政策态度的问题。使用描述性和推断性统计方法对数据进行分析。

结果

大多数受访者表示,如果某种药物在环境方面更具优势,他们愿意开一种效果稍差的药物,疼痛管理和降压方面为77%,避孕方面为50%。与成本、地区治疗指南、给药间隔和用户友好性相比,环境影响在开处方决策中被列为最不重要的因素。共有68%的受访者同意医生在开处方时应考虑环境因素,然而只有少数人在开处方时经常搜索环境信息。针对其他利益相关者(如当局和制药行业)的政策获得了大力支持。

结论

瑞典全科医生在开处方时愿意考虑环境因素。然而,其他因素更常被考虑,并且全科医生将更高的责任归咎于其他行为者。改善获取有关药物的环境信息的渠道有助于更环保地开处方。

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