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药品与环境:一种基于网络的决策支持工具,用于考虑药品使用过程中的环境问题。

Pharmaceuticals and Environment: a web-based decision support for considering environmental aspects of medicines in use.

机构信息

Health and Medical Care Administration, Region Stockholm, Box 6909, SE-102 39, Stockholm, Sweden.

Formerly at Health and Medical Care Administration, Region Stockholm, Stockholm, Sweden.

出版信息

Eur J Clin Pharmacol. 2020 Aug;76(8):1151-1160. doi: 10.1007/s00228-020-02885-1. Epub 2020 May 9.

Abstract

PURPOSE

The database Pharmaceuticals and Environment is a non-commercial, freely available web-based decision support presenting compiled environmental information for pharmaceutical substances. It was developed by Region Stockholm and launched in 2016 at janusinfo.se. The purpose of this paper is to present the database, report on its current use, and reflect on lessons learned from developing and managing the database.

METHODS

A standard operating procedure describes the work and content of the database, e.g., how information is retrieved, processed, and presented. Google Analytics was used for metrics. Issues related to the database have been discussed and handled by a reference group. The experiences from this work are presented.

RESULTS

The database contains environmental hazard and risk information, primarily gathered from regulatory authorities and pharmaceutical companies. There are also assessments comparing substances within some groups of pharmaceuticals. The database is used by the Swedish Drug and Therapeutics Committees to include environmental aspects when recommending pharmaceuticals for health care providers. Page views show that users primarily look for information on commonly used substances, e.g., diclofenac and paracetamol/acetaminophen. Major problems for the development of the database are lack of data, lack of transparency, and discrepancies in the available environmental information.

CONCLUSION

In the absence of an adequate decision support produced by the regulatory authorities, we find the database Pharmaceuticals and Environment to be useful for Swedish Drug and Therapeutics Committees and health care providers, and it is our belief that the information can be valuable also in other settings.

摘要

目的

Pharmaceuticals and Environment 数据库是一个非商业性的、免费提供的基于网络的决策支持工具,为药物物质提供编译后的环境信息。它由斯德哥尔摩地区开发,并于 2016 年在 janusinfo.se 上推出。本文旨在介绍该数据库,报告其当前使用情况,并反思在开发和管理数据库方面的经验教训。

方法

标准操作程序描述了数据库的工作和内容,例如信息的检索、处理和呈现方式。Google Analytics 用于衡量指标。与数据库相关的问题由参考小组讨论和处理。展示了从这项工作中获得的经验。

结果

该数据库包含环境危害和风险信息,主要从监管机构和制药公司收集。还有一些评估是比较某些类别的药物中的物质。该数据库被瑞典药品和治疗委员会用于在向医疗保健提供者推荐药物时纳入环境方面的考虑。页面浏览量显示,用户主要查找常用物质的信息,如双氯芬酸和对乙酰氨基酚/扑热息痛。数据库开发的主要问题是数据缺乏、透明度不足以及可用环境信息存在差异。

结论

在监管机构没有提供足够的决策支持的情况下,我们发现 Pharmaceuticals and Environment 数据库对瑞典药品和治疗委员会以及医疗保健提供者非常有用,我们相信这些信息在其他环境中也可能具有价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7f2/7351842/9b432fc88c2d/228_2020_2885_Fig1_HTML.jpg

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