Takamoto T, Schwartz B
Invest Ophthalmol Vis Sci. 1985 Oct;26(10):1445-9.
The authors have developed an objective, quantitative method for detecting optic disc cup changes that occur with time. Called stereochronometry, this new technique uses a stereoplotter to measure changes recorded in the combination of two single photographs taken of the same optic disc at different times. The reproducibility and sensitivity of stereochronometry were evaluated using a model eye. Stereochronometric measurements were significantly correlated with calibrated changes of depth and width of the cup of the model eye. Standard deviations for five measurements of cup changes without camera shift range from 2 microns to 18 microns, and errors (deviations of the mean of measurements from calibrated cup changes) ranged from -26 microns to +33 microns. Standard deviations and errors in the measurement of cup depth and width were significantly increased when the camera was shifted by 2.5 mm between photographs to simulate possible changes in photographic conditions.
作者开发了一种客观、定量的方法来检测随时间发生的视盘杯状变化。这种名为立体计时法的新技术使用立体绘图仪来测量在不同时间拍摄的同一视盘的两张单张照片组合中记录的变化。使用模型眼对视盘立体计时法的再现性和敏感性进行了评估。视盘立体计时测量与模型眼杯状深度和宽度的校准变化显著相关。在相机无移位情况下对视盘杯状变化进行的五次测量的标准差范围为2微米至18微米，误差（测量平均值与校准杯状变化的偏差）范围为-26微米至+33微米。当两张照片之间相机移位2.5毫米以模拟摄影条件的可能变化时，杯状深度和宽度测量的标准差和误差显著增加。
