Zaher Wael, Marcon Lorenzo, Ebinger Klaus-Richard, Sorgente Antonio
Department of Cardiology, Centre Hospitalier EpiCURA, Hornu, Belgium.
Ann Noninvasive Electrocardiol. 2025 Jul;30(4):e70089. doi: 10.1111/anec.70089.
Ablation of the cavo-tricuspid isthmus (CTI) is the standard treatment for typical atrial flutter. High-power strategies have been described to improve lesion efficacy and durability.
To compare the acute success, safety, and long-term outcomes of two strategies of high-power CTI ablation using 8-mm gold-tip nonirrigated and 4-mm irrigated-tip catheters.
This single-center prospective cohort study included 253 patients who underwent CTI ablation. Patients were treated with either an 8-mm gold-tip nonirrigated catheter (60 W, ≥ 30 s) or a 4-mm irrigated catheter (45 W, ≥ 30 s). Procedural outcomes, safety, and long-term follow-up data were assessed.
Using a propensity score matching, 180 patients were yielded with a 1:1 ratio. Acute bidirectional CTI block was achieved in 97.8% of the 4-mm group and 97.8% of the 8-mm group (p = 1.000). No major complications were reported. During a median follow-up of 27.7 ± 20.1 months, freedom from atrial arrhythmia was 93.3% in both groups (log rank p value 0.935). No significant differences were observed in atrial fibrillation incidence, pacemaker implantation, or cardiovascular mortality between the groups.
High-power CTI ablation with both 8-mm gold-tip nonirrigated and 4-mm irrigated catheters is highly effective and safe, providing durable outcomes over long-term follow-up.
三尖瓣峡部(CTI)消融是典型心房扑动的标准治疗方法。已描述了高能量策略以提高损伤效果和持久性。
比较使用8毫米金头非灌注导管和4毫米灌注头导管的两种高能量CTI消融策略的急性成功率、安全性和长期结果。
这项单中心前瞻性队列研究纳入了253例行CTI消融的患者。患者分别接受8毫米金头非灌注导管(60瓦,≥30秒)或4毫米灌注导管(45瓦,≥30秒)治疗。评估手术结果、安全性和长期随访数据。
采用倾向评分匹配法,按1:1比例产生了180例患者。4毫米组和8毫米组的急性双向CTI阻滞率均为97.8%(p = 1.000)。未报告重大并发症。在中位随访27.7±20.1个月期间,两组的房性心律失常复发率均为93.3%(对数秩p值0.935)。两组之间在房颤发生率、起搏器植入或心血管死亡率方面未观察到显著差异。
使用8毫米金头非灌注导管和4毫米灌注导管进行高能量CTI消融均高度有效且安全,在长期随访中可提供持久的结果。