Prager Logan, Ghayouri Masoumeh, Abbruzzese Thomas A, Fan Ji
General Surgery, HCA Florida Hospital Brandon, Brandon, USA.
Pathology, Moffitt Cancer Center, Tampa, USA.
Cureus. 2025 Apr 29;17(4):e83174. doi: 10.7759/cureus.83174. eCollection 2025 Apr.
This case report describes a rare etiology of a symptomatic small bowel mass that had been causing our patient spontaneous abdominal pain, nausea, and loss of appetite. The patient is a 53-year-old Caucasian male undergoing chemotherapy and radiation for a nasopharyngeal Epstein-Barr virus-positive carcinoma. He presented to the urgent care with two days of sharp upper abdominal pain and nausea without association of symptoms to prior chemotherapy treatments. Workup initially suggested a jejunal hematoma, which was later revealed to be a mass. The patient underwent outpatient robot-assisted laparoscopic resection of the mass. Pathology demonstrated benign ectopic pancreatic tissue invading through the serosa into the muscularis propria with the sampled lymph nodes negative for malignancy. Ectopic pancreas is a rare congenital abnormality most commonly found in the gastrointestinal tract. Most cases are asymptomatic, but epigastric pain is the most common symptom, followed by nausea, vomiting, and hematochezia. While a benign finding, the index of suspicion for malignancy should remain high as diagnosis can be difficult. Ectopic pancreatic tissue is susceptible to the same pathology that may affect a native pancreas, including pancreatitis and pancreatic malignancy. Radiological and endoscopy studies are useful adjuncts that may increase clinical suspicion; however, it is difficult to differentiate ectopic pancreas from a neoplasm without tissue biopsy. Although no standardized approach exists, surgical resection remains a mainstay of diagnosis and treatment, especially in anatomic locations not amenable to endoscopic intervention.
本病例报告描述了一例有症状的小肠肿物的罕见病因,该肿物导致我们的患者出现自发性腹痛、恶心和食欲不振。患者是一名53岁的白人男性,正在接受针对鼻咽部爱泼斯坦-巴尔病毒阳性癌的化疗和放疗。他因上腹部剧痛和恶心两天就诊于紧急护理中心,这些症状与先前的化疗治疗无关。初步检查提示为空肠血肿,后来发现是一个肿物。患者接受了门诊机器人辅助腹腔镜肿物切除术。病理显示良性异位胰腺组织穿透浆膜侵犯固有肌层,所取淋巴结无恶性病变。异位胰腺是一种罕见的先天性异常,最常见于胃肠道。大多数病例无症状,但上腹部疼痛是最常见的症状,其次是恶心、呕吐和便血。虽然是良性发现,但由于诊断可能困难,对恶性肿瘤的怀疑指数仍应很高。异位胰腺组织易受可能影响正常胰腺的相同病理过程影响,包括胰腺炎和胰腺恶性肿瘤。放射学和内镜检查是有用的辅助手段,可能会增加临床怀疑;然而,在没有组织活检的情况下,很难将异位胰腺与肿瘤区分开来。虽然不存在标准化方法,但手术切除仍然是诊断和治疗的主要手段,尤其是在不适合内镜干预的解剖部位。