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司库奇尤单抗治疗泛发性脓疱型银屑病合并Hallopeau连续性肢端皮炎:一例报告及机制探讨

Spesolimab in generalized pustular psoriasis complicated by acrodermatitis continua of Hallopeau: a case report and mechanistic insights.

作者信息

Hou Xin-Yi, Xiao Hai-Lu, Wang Jing-Yu, Zhang Jin, Ren Bo, Niu Chu-Chu, Liu Fei-Fei, Lu Bin

机构信息

Department of Dermatology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.

School of Clinical Medicine, Jining Medical University, Jining, Shandong, China.

出版信息

Front Immunol. 2025 May 15;16:1563553. doi: 10.3389/fimmu.2025.1563553. eCollection 2025.

Abstract

A 62-year-old Chinese woman presented to the hospital for help with generalized pustular psoriasis (GPP) and acrodermatitis continua of Hallopeau (ACH). While conventional treatments failed to achieve significant improvement, the patient received two doses of spesolimab, and the effect was remarkable. No adverse reactions were observed in the follow-up period.

摘要

一名62岁的中国女性因泛发性脓疱型银屑病(GPP)和Hallopeau连续性肢端皮炎(ACH)前往医院寻求帮助。尽管传统治疗未能取得显著改善,但该患者接受了两剂司帕索利单抗,效果显著。随访期间未观察到不良反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57c1/12119614/7087c777bde0/fimmu-16-1563553-g001.jpg

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