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神经外科手术术中神经生理监测病例的运动诱发电位研究

Study of Motor Evoked Potential on Intraoperative Neurophysiological Monitoring Cases of Neurosurgeries.

作者信息

Bajpai Manish, Ojha B K, Verma Dileep Kumar, Saif Afreen, Verma Akhilesh Kumar

机构信息

Department of Physiology, King Georges Medical University, Lucknow, Uttar Pradesh, India.

Department of Neurosurgery, King Georges Medical University, Lucknow, Uttar Pradesh, India.

出版信息

Ann Afr Med. 2025 Jul 1;24(3):617-620. doi: 10.4103/aam.aam_133_24. Epub 2025 May 30.

Abstract

BACKGROUND

Motor evoked potential (MEP) monitoring is crucial in intraoperative neurophysiological monitoring (IONM) during neurosurgeries, but its effectiveness is influenced by factors such as anesthesia type, patient condition, and surgical technique. Interpreting MEP changes requires expertise due to technical issues and neural injury. Clinical studies show MEPs reduce permanent motor deficits, improving surgical outcomes and patient safety. This study aims to evaluate the efficacy and outcomes of MEP monitoring in IONM during neurosurgeries.

METHODS

A cross-sectional study was conducted at King George's Medical University, Lucknow, involving 132 patients undergoing elective surgery and above 2 years of age. The study excluded trauma patients, severely ill patients, morbidly ill patients, and those under 2 years old patients. The study involved subjects from the Department of Neurosurgery at King George's Medical University, Lucknow. Intraoperative neuromonitoring was performed using the Medtronic Nim-Eclipse System. MEP was used to monitor the functional integrity of corticospinal tracts by stimulating the patient's motor cortex transcranially and recording the activity in selected muscles.

RESULTS

Out of 132, a total of 75 (59.09%) patients were male and 57 (40.91%) patients were female. Patient distribution is based on age group, with ≤20 years being the most common age group, followed by 21-30 years, 31-40 years, 41-50 years, 51-60 years, and >60 years, respectively. The neurological impairments observed after surgery in the form of MEP waveforms. Of the 39 patients, 2 individuals (5.13%) had neurological impairment at the end of the procedure.

CONCLUSION

The study suggests that monitoring evoked potentials can detect and address neurological issues, improve postoperation function, and enhance patient safety and surgical outcomes in neurosurgery. It emphasizes the importance of MEP monitoring for assessing motor pathway integrity and recommends further studies with larger cohorts.

摘要

背景

运动诱发电位(MEP)监测在神经外科手术的术中神经生理监测(IONM)中至关重要,但其有效性受到麻醉类型、患者状况和手术技术等因素的影响。由于技术问题和神经损伤,解读MEP变化需要专业知识。临床研究表明,MEP可减少永久性运动功能障碍,改善手术效果并提高患者安全性。本研究旨在评估MEP监测在神经外科手术IONM中的疗效和结果。

方法

在勒克瑙的乔治国王医科大学进行了一项横断面研究,纳入132例接受择期手术且年龄在2岁以上的患者。该研究排除了创伤患者、重症患者、危重病患者和2岁以下患者。研究对象来自勒克瑙乔治国王医科大学神经外科。术中神经监测使用美敦力Nim-Eclipse系统。通过经颅刺激患者的运动皮层并记录选定肌肉的活动,使用MEP监测皮质脊髓束的功能完整性。

结果

132例患者中,共有75例(59.09%)为男性,57例(40.91%)为女性。患者分布基于年龄组,≤20岁是最常见的年龄组,其次分别是21 - 30岁、31 - 40岁、41 - 50岁、51 - 60岁和>60岁。术后以MEP波形形式观察到神经功能障碍。在39例患者中,有2例(5.13%)在手术结束时出现神经功能障碍。

结论

该研究表明,监测诱发电位可检测并解决神经问题,改善术后功能,并提高神经外科手术中的患者安全性和手术效果。它强调了MEP监测对于评估运动通路完整性的重要性,并建议进行更大样本量的进一步研究。

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