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选择性脊神经后根切断术(SDR)中的患者选择

Patient Selection in Selective Dorsal Rhizotomy (SDR).

作者信息

Hall Benjamin J, Gillespie Conor S, Sneade Christine, Quirk Deborah, Hennigan Dawn, Pettorini Benedetta

机构信息

Department of Neurosurgery, Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, UK.

Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, UK.

出版信息

Adv Tech Stand Neurosurg. 2025;51:225-237. doi: 10.1007/978-3-031-86441-4_16.

Abstract

For almost as long as selective dorsal rhizotomy (SDR) has existed, there has been debate surrounding which patients should be eligible to undergo the procedure. The selection criteria used to identify suitable surgical candidates have remained largely unchanged for the last three decades, despite the popularity and use of the procedure increasing. Historically, those aged between 3 and 9 years, those of GMFCS level 2 or 3, and those without evidence of dystonia were considered for SDR. In recent years, as the procedure has continued to develop, however, these parameters are expanding, with evidence to suggest a much broader cohort of patients may benefit from SDR than once thought. This chapter seeks to review current practice in patient selection for SDR, as well as the potential directions that this controversial discussion may move towards in the future.

摘要

自从选择性背根切断术(SDR)出现以来,围绕哪些患者适合接受该手术的争论就一直存在。尽管该手术的普及程度和应用不断增加,但在过去三十年里,用于确定合适手术候选人的选择标准基本没有变化。从历史上看,年龄在3至9岁之间、GMFCS水平为2或3级且无肌张力障碍证据的患者被考虑进行SDR。然而,近年来,随着该手术的不断发展,这些参数正在扩大,有证据表明,可能从SDR中受益的患者群体比以前认为的要广泛得多。本章旨在回顾目前SDR患者选择的实践情况,以及这一有争议的讨论未来可能发展的潜在方向。

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