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2
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Disabil Health J. 2009 Jan;2(1):45-8. doi: 10.1016/j.dhjo.2008.08.001.
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A report: the definition and classification of cerebral palsy April 2006.一份报告:《脑性瘫痪的定义与分类》,2006年4月
Dev Med Child Neurol Suppl. 2007 Feb;109:8-14.
4
Clinical profile and predisposing factors of cerebral palsy.脑瘫的临床特征及诱发因素
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5
The descriptive epidemiology of cerebral palsy.脑瘫的描述性流行病学
Clin Perinatol. 2006 Jun;33(2):251-67. doi: 10.1016/j.clp.2006.03.011.
6
Prevalence of four developmental disabilities among children aged 8 years--Metropolitan Atlanta Developmental Disabilities Surveillance Program, 1996 and 2000.8岁儿童中四种发育障碍的患病率——大亚特兰大发育障碍监测项目,1996年和2000年
MMWR Surveill Summ. 2006 Jan 27;55(1):1-9.
7
Trends in the prevalence of cerebral palsy in a population-based study.一项基于人群的研究中脑瘫患病率的趋势
Pediatrics. 2002 Dec;110(6):1220-5. doi: 10.1542/peds.110.6.1220.
8
Prevalence and characteristics of children with cerebral palsy in Europe.欧洲脑瘫儿童的患病率及特征
Dev Med Child Neurol. 2002 Sep;44(9):633-40.
9
Clinical spectrum of cerebral palsy in north India--an analysis of 1,000 cases.印度北部脑性瘫痪的临床谱——1000例病例分析
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脑瘫儿童的临床谱、合并症及危险因素概况:一项前瞻性研究。

Clinical Spectrum, Comorbidities, and Risk Factor Profile of Cerebral Palsy Children: A Prospective Study.

作者信息

Minocha Priyanka, Sitaraman Sadasivan, Sachdeva Pallavi

机构信息

Department of Pediatrics, Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan, India.

出版信息

J Pediatr Neurosci. 2017 Jan-Mar;12(1):15-18. doi: 10.4103/1817-1745.205622.

DOI:10.4103/1817-1745.205622
PMID:28553372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5437780/
Abstract

AIM AND OBJECTIVE

Cerebral palsy (CP) is the most common motor disability in childhood. This study aimed to describe clinical spectrum, comorbidities, and risk factors associated with CP children.

MATERIALS AND METHODS

This hospital-based observational study was conducted in tertiary level hospital in Jaipur including 180 CP children aged 1-12 years, attending the Paediatric Neurology Outdoor and Child Development Centre. A detailed history of antenatal, natal, and postnatal events taken and thorough examination was performed to stratify children in proper topographical and physiological classification.

RESULTS

Mothers of 47.7% CP children were primigravida and 17.7% mothers had anemia during pregnancy. Among natal factors, asphyxia contributed to maximum cases (52.2%). Seizure in postnatal life was the second most common risk factor for CP after asphyxia. Spastic CP (84.4%) was the most common physiological type, and quadriplegia (56.6%) was the most common topographical type observed in this study. Intellectual disability (47.7%) followed by epilepsy (41.6%) was the most common comorbidity.

CONCLUSION

Even with the advancement of health-care system, asphyxia is the most common risk factor, and spastic quadriplegia is the most common type of CP. There is still a need of improving the health facilities to overcome this costly and common neuromotor disability. Widespread knowledge of common risk factors that can predispose to CP can prevent the CP development to some extent and knowledge of clinical spectrum, and comorbidities can improve their targeted treatment which can improve their growth and social participation.

摘要

目的

脑性瘫痪(CP)是儿童期最常见的运动障碍。本研究旨在描述与CP患儿相关的临床谱、合并症及危险因素。

材料与方法

本基于医院的观察性研究在斋浦尔的一家三级医院进行,纳入了180名年龄在1至12岁、就诊于儿科神经科门诊及儿童发育中心的CP患儿。详细记录产前、产时及产后事件的病史,并进行全面检查,以便根据合适的解剖部位和生理分类对患儿进行分层。

结果

47.7%的CP患儿母亲为初产妇,17.7%的母亲在孕期患有贫血。在产时因素中,窒息导致的病例最多(52.2%)。出生后癫痫是继窒息之后CP的第二大常见危险因素。痉挛型CP(84.4%)是最常见的生理类型,四肢瘫(56.6%)是本研究中最常见的解剖部位类型。智力障碍(47.7%)其次是癫痫(41.6%)是最常见的合并症。

结论

即使在医疗保健系统不断进步的情况下,窒息仍是最常见的危险因素,痉挛性四肢瘫是CP最常见的类型。仍需要改善卫生设施以克服这种代价高昂且常见的神经运动障碍。广泛了解可能导致CP的常见危险因素可在一定程度上预防CP的发生,了解临床谱及合并症可改善其针对性治疗,从而促进其生长及社会参与。