Reiss A L
J Clin Psychiatry. 1985 Oct;46(10):441-3.
Bipolar affective disorder is not commonly reported in prepubertal children. This may be secondary to age-related variability in patterns of symptomatology, lack of appropriate diagnostic criteria, and/or confusion with other psychiatric disorders of childhood. A case of adult-type bipolar disorder in a prepubertal child is presented, with emphasis on developmental history, genetic influences, and response to pharmacologic intervention. Studies of children affected by, or at risk for, bipolar disorder are needed to identify biologic and developmental markers of this syndrome.
双相情感障碍在青春期前儿童中并不常见。这可能继发于症状模式的年龄相关变异性、缺乏适当的诊断标准，和/或与其他儿童精神障碍相混淆。本文介绍了一名青春期前儿童患成人型双相情感障碍的病例，重点关注发育史、遗传影响和药物干预反应。需要对受双相情感障碍影响或有患双相情感障碍风险的儿童进行研究，以确定该综合征的生物学和发育标志物。
