面向临床医生的微生物组学

The microbiome for clinicians.

作者信息

Porcari Serena, Ng Siew C, Zitvogel Laurence, Sokol Harry, Weersma Rinse K, Elinav Eran, Gasbarrini Antonio, Cammarota Giovanni, Tilg Herbert, Ianiro Gianluca

机构信息

Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore Facoltà di Medicina e Chirurgia, Roma, Italy; Department of Medical and Surgical Sciences, UOC Gastroenterologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy; Department of Medical and Surgical Sciences, UOC CEMAD Centro Malattie dell'Apparato Digerente, Medicina Interna e Gastroenterologia, Fondazione Policlinico Universitario Gemelli IRCCS, Roma, Italy.

Microbiota I-Center (MagIC), Hong Kong, China; Department of Medicine and Therapeutics, Centre for Gut Microbiota Research, The Chinese University of Hong Kong, Hong Kong, China; New Cornerstone Science Laboratory, The Chinese University of Hong Kong, Hong Kong, China.

出版信息

Cell. 2025 May 29;188(11):2836-2844. doi: 10.1016/j.cell.2025.04.016.

DOI:10.1016/j.cell.2025.04.016

PMID:40446358

Abstract

Despite promising evidence in diagnostics and therapeutics, microbiome research is not yet implemented into clinical medicine. Several initiatives, including the standardization of microbiome research, the refinement of microbiome clinical trial design, and the development of communication between microbiome researchers and clinicians, are crucial to move microbiome science toward clinical practice.

摘要

尽管在诊断和治疗方面有令人鼓舞的证据，但微生物组研究尚未应用于临床医学。包括微生物组研究的标准化、微生物组临床试验设计的完善以及微生物组研究人员与临床医生之间沟通的发展在内的多项举措，对于推动微生物组科学走向临床实践至关重要。