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资源匮乏地区产后高血压疾病血压监测的可行性

Feasibility of Postpartum Blood Pressure Monitoring for Hypertensive Disorders in a Low-Resource Setting.

作者信息

Mahmoud Zainab, Okoye Chukwuebuka F, Orji Adaego A, Ameh Friday O, Nartey Cecilia, Akaba Godwin, Ekele Bissallah A, Jamro Erica L, Lindley Kathryn J, Ojji Dike B, Huffman Mark D

机构信息

Cardiovascular Division and Global Health Center, Department of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA.

Cardiovascular Research Unit, University of Abuja and University of Abuja Teaching Hospital, Abuja, Nigeria.

出版信息

JACC Adv. 2025 May;4(5):101739. doi: 10.1016/j.jacadv.2025.101739.

Abstract

BACKGROUND

Hypertensive disorders of pregnancy (HDP) pose significant risks to maternal health globally, especially in Nigeria, which has the highest maternal mortality rate. Home blood pressure (BP) monitoring is a promising approach for managing HDP.

OBJECTIVES

This study assessed the feasibility of a postpartum home BP-monitoring program for women with HDP in low-resource settings like Nigeria, focusing on recruitment, retention, and fidelity to monitoring protocols. HDP diagnoses associated with persistent hypertension were also assessed.

METHODS

Participants with HDP were enrolled into a prospective cohort. They were educated on BP monitoring and transmitted daily BP readings for 2 weeks. A control group of healthy postpartum women was also enrolled. The 12-week study involved assessments at prespecified intervals.

RESULTS

The study met its target of 90 participants (mean age: 30 years) and had high fidelity (96%) to daily BP recordings and retention (94%) at 12 weeks. The mean systolic BP decreased from 137 mm Hg to 125 mm Hg, and the mean diastolic BP decreased from 89 mm Hg to 84 mm Hg. During the initial 2-week period, 81.1% of normotensive participants experienced elevated BP, with 86.5% showing elevated BP over 12 weeks. In addition, 22% reported adverse cardiovascular events.

CONCLUSIONS

The study demonstrates the feasibility of a postpartum BP-monitoring program in a low-resource setting like Nigeria, with high recruitment, fidelity, and retention. Continued monitoring beyond the immediate postpartum period is essential for improving outcomes. Further research is needed to evaluate the long-term effectiveness and scalability of such programs.

摘要

背景

妊娠高血压疾病(HDP)在全球范围内对孕产妇健康构成重大风险,尤其是在孕产妇死亡率最高的尼日利亚。家庭血压监测是管理HDP的一种有前景的方法。

目的

本研究评估了在尼日利亚等资源匮乏地区为患有HDP的女性开展产后家庭血压监测项目的可行性,重点关注招募、留存率以及对监测方案的依从性。还评估了与持续性高血压相关的HDP诊断情况。

方法

患有HDP的参与者被纳入前瞻性队列研究。对他们进行血压监测方面的教育,并让他们连续2周每天传输血压读数。还纳入了一组健康的产后女性作为对照组。这项为期12周的研究在预定的时间间隔进行评估。

结果

该研究达到了90名参与者的目标(平均年龄:30岁),在12周时对每日血压记录的依从性较高(96%),留存率也较高(94%)。平均收缩压从137毫米汞柱降至125毫米汞柱,平均舒张压从89毫米汞柱降至84毫米汞柱。在最初的2周内,81.1%的血压正常参与者出现血压升高,在12周内有86.5%的人血压升高。此外,22%的人报告了不良心血管事件。

结论

该研究证明了在尼日利亚这样的资源匮乏地区开展产后血压监测项目的可行性,招募率、依从性和留存率都很高。产后立即进行持续监测对于改善结局至关重要。需要进一步研究来评估此类项目的长期有效性和可扩展性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99b6/12235407/bc6982559bd2/ga1.jpg

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