通过萃取烷基化直接测定尿液中的己二酸。

Direct determination of adipic acid in urine by extractive alkylation.

作者信息

Adinolfe N A, Bicking M K

出版信息

J Chromatogr Sci. 1985 Sep;23(9):407-10. doi: 10.1093/chromsci/23.9.407.

DOI:10.1093/chromsci/23.9.407

Abstract

Extractive alkylation procedures are shown to be inhibited by low levels of Cl-. The chloride concentration may be reduced by mercury(II) complexation and dilution. The mercury(II) also enhances the reaction yield through some undetermined mechanism. Minor modifications of procedures for standards allow direct determination of adipic acid in urine.

摘要

萃取烷基化程序显示会受到低水平氯离子（Cl⁻）的抑制。可通过汞（II）络合和稀释来降低氯化物浓度。汞（II）还通过某种未确定的机制提高反应产率。对标准程序进行微小修改后可直接测定尿液中的己二酸。