Roessler Karl, Weiss Jonathan, Shawarba Julia, Quinot Valerie, Kasprian Gregor, Niederle Martin, Czech Thomas, Mayer Florian, Dorfer Christian, Feucht Martha
Neurosurgical Department, Medical University of Vienna, 1090, Vienna, Austria.
Comprehensive Center of Clinical Neurosciences and Mental Health (C3 N-MH), Medical University of Vienna, 1090, Vienna, Austria.
Childs Nerv Syst. 2025 May 30;41(1):195. doi: 10.1007/s00381-025-06857-7.
Hemispherotomy in infants under the age of 3 months is considered a high-risk procedure and is not routinely performed. A 2.5-month-old female infant weighing 5.1 kg successfully underwent a right vertical hemispherotomy after developing status epilepticus due to a right hemispheric Sturge-Weber meningo-angiomatosis. The surgical technique involved skull fixation at the skull base using kid pins to facilitate image-guided surgery with neuronavigation and augmented reality within the eyepiece of the microscope employing the vertical hemispherotomy technique. The surgical course was uneventful, with moderate blood loss (100 mL of red blood cells, 90 mL of fresh frozen plasma, and 150 mg of tranexamic acid transfused). The surgery duration was within 2 h. Postoperatively, seizures ceased immediately, and the infant experienced rapid developmental and neurological progress, remaining seizure-free for 8 months after surgery (Engel 1a) now.
3个月以下婴儿的大脑半球切除术被认为是一种高风险手术,通常不会进行。一名体重5.1千克、2.5个月大的女婴因右侧大脑半球斯特奇-韦伯综合征脑膜血管瘤病发生癫痫持续状态后,成功接受了右侧垂直大脑半球切除术。手术技术包括在颅底使用儿童针进行颅骨固定,以便在显微镜目镜内通过神经导航和增强现实技术进行图像引导手术,并采用垂直大脑半球切除术技术。手术过程顺利,术中失血适中(输注了100毫升红细胞、90毫升新鲜冰冻血浆和150毫克氨甲环酸)。手术持续时间在2小时以内。术后,癫痫立即停止,婴儿发育和神经功能迅速改善,术后8个月无癫痫发作(目前为恩格尔1a级)。