Bergdahl S, Ekengren K, Eriksson M
J Pediatr Orthop. 1985 Sep-Oct;5(5):564-8.
The findings in 40 infants with neonatal osteomyelitis were examined to evaluate factors that may predict the development of sequelae. On follow-up at 1-11 years of age, 16 children were found to have moderate (six) and severe (10) sequelae. Thirteen of these 16 children were among the 21 infants who had perinatal risk factors. On the other hand, there were only three handicapped infants in the group of 19 who had no risk factors. The high-risk infants were, on the average, younger at onset of osteomyelitis than the previously healthy babies. No differences were found between those two groups that could be ascribed to the causative organisms. Fifty-five osteomyelitic sites involving the large joints were diagnosed. Growth disturbance was evident in 20 of 36 nonoperated foci and four of 19 operated foci. To achieve the best result, the joint and abscess should be drained, and this should be supplemented by drainage of the metaphysis.
对40例新生儿骨髓炎患儿的研究结果进行分析，以评估可能预测后遗症发生的因素。在1至11岁的随访中，发现16名儿童有中度（6例）和重度（10例）后遗症。这16名儿童中有13名在21例有围产期危险因素的婴儿中。另一方面，在19名无危险因素的婴儿组中只有3名残疾婴儿。高危婴儿骨髓炎发病时的平均年龄比之前健康的婴儿小。两组之间在致病微生物方面未发现差异。共诊断出55个累及大关节的骨髓炎部位。在36个未手术病灶中的20个以及19个手术病灶中的4个出现生长障碍。为了获得最佳效果，应引流关节和脓肿，并辅以干骺端引流。
