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Unraveling the diversity of bile acid modifications by integrative mass spectrometry approaches.

作者信息

Xing Nan, Wang Yu-Fei, Ding Xue, Tan Hong-Li, Li Yi-Fang, Sun Guo-Xiang, He Rong-Rong, Sun Wan-Yang

机构信息

State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs, Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility, Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products, International Cooperative Laboratory of TCM Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, 510632, China.

School of Pharmacy, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China.

出版信息

Sci China Life Sci. 2025 May 27. doi: 10.1007/s11427-025-2909-3.

DOI:10.1007/s11427-025-2909-3
PMID:40448906
Abstract
摘要

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本文引用的文献

[1]
Host metabolism balances microbial regulation of bile acid signalling.

Nature. 2025-2

[2]
Structure-guided discovery of bile acid derivatives for treating liver diseases without causing itch.

Cell. 2024-12-12

[3]
How bile acids and the microbiota interact to shape host immunity.

Nat Rev Immunol. 2024-11

[4]
TNF compromises intestinal bile-acid tolerance dictating colitis progression and limited infliximab response.

Cell Metab. 2024-9-3

[5]
Gut symbionts alleviate MASH through a secondary bile acid biosynthetic pathway.

Cell. 2024-5-23

[6]
Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8 T cell effector functions.

Immunity. 2024-4-9

[7]
The underappreciated diversity of bile acid modifications.

Cell. 2024-3-28

[8]
Gut commensal Christensenella minuta modulates host metabolism via acylated secondary bile acids.

Nat Microbiol. 2024-2

[9]
Reverse metabolomics for the discovery of chemical structures from humans.

Nature. 2024-2

[10]
Profiling the human intestinal environment under physiological conditions.

Nature. 2023-5

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