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单侧三角纤维软骨复合体损伤时旋前旋后过程中基于四维计算机断层扫描的桡尺远侧关节骨运动学

Four-dimensional computed tomography-derived distal radioulnar joint osteokinematics during pronosupination with unilateral triangular fibrocartilage complex injuries.

作者信息

Trentadue Taylor P, Lopez Cesar, Thoreson Andrew, Foley Robert A, Weber Nikkole M, Holmes David R, An Kai-Nan, Leng Shuai, Zhao Kristin D, Kakar Sanjeev

机构信息

Assistive and Restorative Technology Laboratory, Rehabilitation Medicine Research Center, Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA; Mayo Clinic Medical Scientist Training Program, Mayo Clinic, Rochester, MN, USA; Mayo Clinic Graduate Program in Biomedical Engineering and Physiology, Mayo Clinic, Rochester, MN, USA.

Assistive and Restorative Technology Laboratory, Rehabilitation Medicine Research Center, Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA.

出版信息

J Biomech. 2025 Jul;188:112703. doi: 10.1016/j.jbiomech.2025.112703. Epub 2025 Apr 16.

Abstract

The distal radioulnar joint (DRUJ) is a load-bearing joint that permits pronosupination of the forearm. Pronosupination may provoke instability following injuries to the soft tissue stabilizers of the joint, particularly when loaded against resistance. The objective of this study was to assess osteokinematics between the radius and ulna during pronosupination in 12 participants with suspected unilateral DRUJ injury enrolled in a prospective study using four-dimensional computed tomography (4DCT) at baseline and six months after arthroscopic surgery. We hypothesized that inter-landmark distances between the ulnar styloid and three landmarks on the distal radius-the central reference point, dorsal corner, and volar corner-would be related to relative pronosupination position, wrist injury status (injured versus uninjured), application of load (unresisted versus resisted), and timepoint (preoperative versus postoperative). Generalized linear mixed effects models were created to assess the change in inter-landmark distances with different levels of the predictor variables. Inter-landmark distances at all three radius landmarks were significantly associated with pronosupination angle and application of resistance. The effects of injury and surgery were less consistent and, if present, significant at only the volar corner landmark. The random effect for participant was statistically significant in all models. 4DCT-derived osteokinematics reflect position in the pronosupination arc and the application of resistance. However, the effect of injury or intervention was not statistically significant in the majority of single-landmark models. This suggests that 4DCT detects changes in biomechanical phenomena, although more sophisticated biomarkers may be justified for injury classification.

摘要

桡尺远侧关节(DRUJ)是一个承重关节,可使前臂进行旋前和旋后动作。在该关节的软组织稳定器受伤后,尤其是在有阻力负荷的情况下,旋前和旋后动作可能会引发不稳定。本研究的目的是,在一项前瞻性研究中,使用四维计算机断层扫描(4DCT),在基线期及关节镜手术后6个月,评估12名疑似单侧桡尺远侧关节损伤参与者在旋前和旋后过程中桡骨和尺骨之间的骨运动学。我们假设,尺骨茎突与桡骨远端三个标志点(中央参考点、背侧角和掌侧角)之间的标志点间距,会与相对旋前和旋后位置、腕部损伤状态(受伤与未受伤)、负荷应用情况(无阻力与有阻力)以及时间点(术前与术后)相关。创建广义线性混合效应模型,以评估不同预测变量水平下标志点间距的变化。桡骨所有三个标志点处的标志点间距均与旋前和旋后角度以及阻力应用显著相关。损伤和手术的影响不太一致,即使有影响,也仅在掌侧角标志点处显著。参与者的随机效应在所有模型中均具有统计学意义。4DCT得出的骨运动学反映了旋前和旋后弧中的位置以及阻力的应用。然而,在大多数单标志点模型中,损伤或干预的影响在统计学上并不显著。这表明,4DCT能检测到生物力学现象的变化,不过对于损伤分类而言,可能需要更复杂的生物标志物。

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