Kim Dae Hee, Lew Helen, Rah Sang Hoon, Yoo Yung-Ju, Ahn Hyosook, Kim Ungsoo S, Lee Jung Ho, Lee Se-Youp
Department of Ophthalmology, Kim's Eye Hospital, Seoul, Korea.
CHA University Medical College Bundang CHA Medical Center, Seongnam, Korea.
Graefes Arch Clin Exp Ophthalmol. 2025 May 31. doi: 10.1007/s00417-025-06758-0.
To investigate clinical features of intermittent exotropia (IXT) according to fusional control status from the Korean Intermittent Exotropia Multicenter Study (KIEMS).
A total of 2715 IXT participants from the KIEMS dataset were included in this study. We collected age, sex, best corrected visual acuity in LogMAR (BCVA), cycloplegic refraction data, exotropia angle and fusional control status, and near stereoacuity. Exotropia types were classified into basic, convergence insufficiency (CI) and divergence excess (DE) types. Distributions of exotropia type and sex according to fusional control status were investigated. Age, BCVA, spherical equivalents, exotropia angle and near stereoacuity were compared according to fusional control status.
Female to male ratio was 1316 (48.5%) to 1399 (51.5%). Mean age of the participants was 9.4 ± 6.4 years. Mean exotropia angle was 22.5 ± 8.8 and 24.8 ± 9.4 prism diopters at distant and near fixation. Fusional control status was better in CI at distant and DE at near (P = 0.002, 0.021 each). Distant and near exotropia angle were larger in patients with worse distant and near control (P < 0.001). Near stereoacuity was also worse in patients with worse distant and near control (P < 0.001). Good distant control patients had more myopic SE (P < 0.001). Poor near control patients showed worse BCVA and larger BCVA difference (P < 0.001).
Fusional control was highly associated with exotropia type and angle, near stereoacuity, and visual acuity. Near fusional control was associated with mean and difference of BCVA in both eyes.
根据韩国间歇性外斜视多中心研究（KIEMS）中的融合控制状态，探讨间歇性外斜视（IXT）的临床特征。
本研究纳入了KIEMS数据集中的2715例IXT参与者。我们收集了年龄、性别、LogMAR视力表测量的最佳矫正视力（BCVA）、睫状肌麻痹验光数据、外斜视角度和融合控制状态，以及近立体视锐度。外斜视类型分为基本型、集合不足（CI）型和分开过强（DE）型。研究了根据融合控制状态的外斜视类型和性别的分布情况。根据融合控制状态比较年龄、BCVA、球镜等效度数、外斜视角度和近立体视锐度。
女性与男性的比例为1316例（48.5%）比1399例（51.5%）。参与者的平均年龄为9.4±6.4岁。远距离和近距离注视时的平均外斜视角度分别为22.5±8.8和24.8±9.4棱镜度。CI型在远距离时和DE型在近距离时的融合控制状态更好（P值分别为0.002和0.021）。远距离和近距离控制较差的患者，其远距离和近距离外斜视角度更大（P<0.001）。远距离和近距离控制较差的患者，其近立体视锐度也更差（P<0.001）。远距离控制良好的患者近视球镜等效度数更高（P<0.001）。近距离控制较差的患者BCVA更差，且BCVA差异更大（P<0.001）。
融合控制与外斜视类型、角度、近立体视锐度和视力密切相关。近距离融合控制与双眼BCVA的平均值和差值有关。
