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胸腰椎手术中脊柱骨盆参数与术后尿潴留的相关性:一项倾向匹配分析

Association between spinopelvic parameters and postoperative urinary retention in thoracolumbar spine surgery: a propensity-matched analysis.

作者信息

Lee Jaenam, Suk Kyung Soo, Lee Byung Ho, Park Si Young, Kim Hak Sun, Moon Seoung Hwan, Park Sub-Ri, Kim Namhoo, Shin Jae Won, Kwon Ji-Won

机构信息

Department of Orthopedic Surgery, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

出版信息

Sci Rep. 2025 Jun 1;15(1):19200. doi: 10.1038/s41598-025-04127-9.

Abstract

Postoperative urinary retention (POUR) is a frequent complication following spine surgery, with reported incidence rates ranging from 5 to 70%. While numerous risk factors have been identified, the relationship between spinopelvic parameters and POUR has not been previously investigated. This retrospective study examined the potential association between spinopelvic alignment and POUR in patients undergoing thoracolumbar spine surgery. We analyzed data from 420 patients who underwent surgery for degenerative thoracolumbar conditions between March 2021 and February 2024. After applying exclusion criteria and performing propensity score matching, 190 patients (95 with POUR, 95 without POUR) were included in the final analysis. Radiological parameters, including lumbar lordosis (LL), lower lumbar lordosis (LLL), pelvic tilt, sacral slope, and pelvic incidence, were assessed using preoperative and postoperative standing radiographs. Multivariable logistic regression analysis identified decreased preoperative LLL (< 27.77°) as an independent predictor of POUR (OR = 2.08, 95% CI = 1.10-3.91, p = 0.024). Additionally, higher intraoperative mean arterial pressure (> 75.35 mmHg) was associated with increased POUR risk (OR = 2.73, 95% CI = 1.08-6.88, p = 0.033). Our findings suggest that spinopelvic alignment, particularly decreased LLL, may play a previously unrecognized role in the development of POUR following thoracolumbar spine surgery. This novel association expands our understanding of POUR pathophysiology and could inform preoperative risk assessment and perioperative management strategies. Future prospective studies are warranted to validate these findings and explore the underlying mechanisms.

摘要

术后尿潴留(POUR)是脊柱手术后常见的并发症,报道的发生率在5%至70%之间。虽然已确定了众多风险因素,但脊柱骨盆参数与POUR之间的关系此前尚未得到研究。这项回顾性研究探讨了胸腰椎手术患者脊柱骨盆对线与POUR之间的潜在关联。我们分析了2021年3月至2024年2月期间因退行性胸腰椎疾病接受手术的420例患者的数据。在应用排除标准并进行倾向得分匹配后,最终分析纳入了190例患者(95例发生POUR,95例未发生POUR)。使用术前和术后站立位X线片评估包括腰椎前凸(LL)、下腰椎前凸(LLL)、骨盆倾斜、骶骨倾斜度和骨盆入射角在内的放射学参数。多变量逻辑回归分析确定术前LLL降低(<27.77°)是POUR的独立预测因素(OR = 2.08,95%CI = 1.10 - 3.91,p = 0.024)。此外,术中平均动脉压较高(>75.35 mmHg)与POUR风险增加相关(OR = 2.73,95%CI = 1.08 - 6.88,p = 0.033)。我们的研究结果表明,脊柱骨盆对线,尤其是LLL降低,可能在胸腰椎手术后POUR的发生中起了之前未被认识到的作用。这种新的关联扩展了我们对POUR病理生理学的理解,并可为术前风险评估和围手术期管理策略提供参考。未来有必要进行前瞻性研究以验证这些发现并探索潜在机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2815/12127435/6c6fabe81804/41598_2025_4127_Fig1_HTML.jpg

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