Arul Devah Lohini, Rodgers William, Ali Enamul, Suchak Krishna
Homerton University Hospital, Homerton Row, London, E9 6SR UK.
Royal London Hospital, London, UK.
J Maxillofac Oral Surg. 2025 Jun;24(3):835-838. doi: 10.1007/s12663-025-02522-3. Epub 2025 Mar 21.
Numerous diseases can manifest with lesions in the oral cavity. It is important for clinicians to be able to assess, diagnose and treat lesions presenting in the oral cavity. A 28-year-old female, presented to the Maxillofacial clinic with an unusual erythematous area on her hard palate. Clinical examination revealed an inflamed, erythematous granulomatous lesion covering most of the hard palate. A biopsy of the palatal lesion was carried out which revealed ulceration with dense plasmacytic aggregates and necrotizing granulomatous inflammation. Acid-fast bacilli were noted on Ziehl-Neelsen stain, supporting the diagnosis of tuberculosis. Diagnosis of oral tuberculosis can be challenging as it rarely presents without a pre-existing diagnosis or symptoms of pulmonary tuberculosis. This case highlights the importance of a broad differential diagnosis, a systematic approach to evaluation, and the role of histopathology in diagnosing uncommon presentations like oral tuberculosis.
许多疾病都可能在口腔出现病变。临床医生能够评估、诊断和治疗口腔出现的病变非常重要。一名28岁女性前往颌面诊所就诊，其硬腭有一处异常的红斑区域。临床检查发现一个发炎的、红斑性肉芽肿病变覆盖了大部分硬腭。对腭部病变进行了活检，结果显示有溃疡形成，伴有密集的浆细胞聚集和坏死性肉芽肿性炎症。齐-尼氏染色发现抗酸杆菌，支持结核病的诊断。口腔结核病的诊断可能具有挑战性，因为它很少在没有先前肺结核诊断或症状的情况下出现。该病例凸显了广泛鉴别诊断、系统评估方法以及组织病理学在诊断像口腔结核病这种罕见表现中的作用。
