Monarchi Gabriele, Gobbo Margherita, Guarda Nardini Luca
Unit of Oral and Maxillofacial Surgery, Ca' Foncello Hospital, 31100, Treviso, Italy.
Department of medicine, Section of maxillo-facial surgery, University of Siena, Viale Bracci, 53100, Siena, Italy.
Eur Arch Otorhinolaryngol. 2025 Jun 2. doi: 10.1007/s00405-025-09484-9.
This study evaluates the prognostic value of ultra-high frequency ultrasonography (UHF-US) in assessing the depth of invasion (DOI) in early-stage tongue squamous cell carcinoma (OSCC). Given the limitations of traditional imaging techniques such as magnetic resonance (MRI) and computed tomography (CT), UHF-US offers a high-resolution alternative for preoperative DOI estimation.
UHF-US demonstrated in literature a high level of accuracy in preoperative DOI measurement, offering improved precision over MRI and CT. The study findings reinforce the clinical importance of DOI as a predictor of nodal metastasis risk and patient outcomes. UHF-US exhibited strong sensitivity and specificity, supporting its role as a valuable tool in guiding surgical decisions.
The study confirms the prognostic significance of DOI in early-stage tongue OSCC and highlights UHF-US as a highly accurate imaging modality for preoperative DOI assessment. UHF-US could play a crucial role in surgical decision-making and patient selection for elective neck dissection. Further research will be needed to validate these findings and explore their practical application in the management of as many oral malignant lesions as possible.
本研究评估超高频率超声(UHF-US)在评估早期舌鳞状细胞癌(OSCC)浸润深度(DOI)方面的预后价值。鉴于传统成像技术如磁共振成像(MRI)和计算机断层扫描(CT)存在局限性,UHF-US为术前DOI评估提供了一种高分辨率的替代方法。
文献表明,UHF-US在术前DOI测量中具有较高的准确性,比MRI和CT具有更高的精度。研究结果强化了DOI作为淋巴结转移风险和患者预后预测指标的临床重要性。UHF-US表现出很强的敏感性和特异性,支持其作为指导手术决策的有价值工具的作用。
该研究证实了DOI在早期舌OSCC中的预后意义,并强调UHF-US作为术前DOI评估的一种高度准确的成像方式。UHF-US在手术决策和选择性颈清扫的患者选择中可能发挥关键作用。需要进一步的研究来验证这些发现,并探索它们在尽可能多的口腔恶性病变管理中的实际应用。