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加速康复外科(ERAS)路径护理对胃肠手术患者术后康复的影响:一项荟萃分析

Effect of ERAS pathway nursing on postoperative rehabilitation of patients undergoing gastrointestinal surgery: a meta-analysis.

作者信息

Dong Fengying, Li Yan, Jin Wenxia, Qiu Zhebing

机构信息

Department of Gastrointestinal Vascular Surgery, Shengzhou People's Hospital, Shengzhou, Zhejiang, 312400, China.

出版信息

BMC Surg. 2025 Jun 2;25(1):239. doi: 10.1186/s12893-025-02976-9.

Abstract

BACKGROUND

This study aimed to systematically evaluate the impact of the Enhanced Recovery After Surgery (ERAS) pathway on postoperative outcomes-including hospital length of stay, complication rates, readmission, reoperation, and mortality-in patients undergoing gastrointestinal surgery, to provide evidence-based guidance for clinical practice.

METHODS

We systematically searched PubMed, Cochrane Library, Embase, Web of Science and Scopus databases for randomized controlled trials (RCTs) and cohort studies on ERAS pathway in postoperative rehabilitation. Thirteen studies comprising a total of 5,603 patients were included. Literature screening and quality assessment followed the standards of Cochrane Collaboration and Newcastle-Ottawa scales. Statistical analysis was performed using R software to calculate the relative risk (RR), mean difference (MD) with 95% confidence interval (CI), and heterogeneity through the I² statistic, with significance set at P < 0.05. This systematic review and meta-analysis has been registered in the PROSPERO database (ID: CRD42024608876).

RESULTS

The ERAS pathway significantly shortened the postoperative hospital stay (MD = -3.16, 95% CI [-4.10, -2.21], P < 0.01) and reduced the incidence of postoperative complications (RR = 0.70, 95% CI [0.58, 0.84], P < 0.01). It also significantly reduced the readmission rates (RR = 0.75, 95% CI [0.58, 0.96], P = 0.02). However, there was no statistically significant difference in the impact of ERAS pathway on reoperation rate and mortality (RR = 0.59, 95% CI [0.01, 30.14], P = 0.62).

CONCLUSIONS

ERAS protocols are associated with improved postoperative recovery in gastrointestinal surgery, including shorter hospital stays and reduced complication and readmission rates. Although no significant effects were found for reoperation or mortality, the overall evidence supports the broader clinical adoption of ERAS, with a need for further high-quality studies to address remaining uncertainties.

摘要

背景

本研究旨在系统评估术后加速康复(ERAS)路径对接受胃肠手术患者术后结局(包括住院时间、并发症发生率、再入院率、再次手术率和死亡率)的影响,为临床实践提供循证指导。

方法

我们系统检索了PubMed、Cochrane图书馆、Embase、Web of Science和Scopus数据库,以查找关于ERAS路径在术后康复方面的随机对照试验(RCT)和队列研究。纳入了13项研究,共5603例患者。文献筛选和质量评估遵循Cochrane协作网和纽卡斯尔-渥太华量表的标准。使用R软件进行统计分析,计算相对风险(RR)、平均差(MD)及其95%置信区间(CI),并通过I²统计量评估异质性,显著性设定为P < 0.05。本系统评价和荟萃分析已在PROSPERO数据库注册(注册号:CRD42024608876)。

结果

ERAS路径显著缩短了术后住院时间(MD = -3.16,95% CI [-4.10, -2.21],P < 0.01),并降低了术后并发症的发生率(RR = 0.70,95% CI [0.58, 0.84],P < 0.01)。它还显著降低了再入院率(RR = 0.75,95% CI [0.58, 0.96],P = 0.02)。然而,ERAS路径对再次手术率和死亡率的影响无统计学显著差异(RR = 0.59,95% CI [0.01, 30.14],P = 0.62)。

结论

ERAS方案与胃肠手术术后恢复改善相关,包括缩短住院时间、降低并发症和再入院率。虽然未发现对再次手术或死亡率有显著影响,但总体证据支持更广泛地在临床中采用ERAS,仍需要进一步的高质量研究来解决剩余的不确定性。

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