Baram Sara, Thomsen Carsten Eckhart, Øzhayat Esben Boeskov, Karlsborg Merete, Bakke Merete
Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Department of Neurology, Bispebjerg Hospital, Copenhagen, Denmark.
J Oral Rehabil. 2025 Oct;52(10):1829-1838. doi: 10.1111/joor.14044. Epub 2025 Jun 2.
Parkinson's disease (PD) affects the motor system of the body; however, there is limited understanding of how the disease impacts the complex interaction of the masticatory muscles.
The purpose of this study is to investigate the maximum muscle output of the masticatory muscles during natural functions.
This clinical case-control study included persons with PD and age- and gender-matched controls without PD. The masticatory muscle output was evaluated by bite force and bilateral surface electromyography. Electromyographic recordings were conducted from the anterior temporal, masseter and digastric muscles during chewing and maximum voluntary contraction (MVC) during maximal intercuspal biting (MVC biting) and maximal jaw opening (MVC opening). Statistical analyses included χ-test, Mann-Whitney U test and Spearman's rank correlation analysis (significance level p < 0.05).
The study included 20 persons with PD (median age: 68.5 years) and 20 persons without PD (median age: 67 years). No significant differences were found between the groups in terms of demographics, teeth present, or bite force measurements. The activity in the masseter muscle was significantly lower in the PD group during MVC biting. The PD group utilised 82% of their masseter muscle MVC during chewing, whereas the control group used 49% of theirs. Additionally, a negative correlation was observed between the severity of PD and the bite force and digastric muscle activity during MVC opening.
These findings indicate that PD may alter the activity patterns of the masticatory muscles during function. This new understanding can be utilised to design targeted interventions aimed at improving orofacial function for this patient group.
帕金森病（PD）会影响身体的运动系统；然而，对于该疾病如何影响咀嚼肌的复杂相互作用，人们了解有限。
本研究旨在调查咀嚼肌在自然功能状态下的最大肌肉输出。
本临床病例对照研究纳入了帕金森病患者以及年龄和性别匹配的非帕金森病对照者。通过咬合力和双侧表面肌电图评估咀嚼肌输出。在咀嚼过程中以及最大牙尖交错咬合（最大咬合时的最大自主收缩，MVC咬合）和最大张口（MVC张口）时的最大自主收缩期间，从前颞肌、咬肌和二腹肌进行肌电图记录。统计分析包括χ检验、曼-惠特尼U检验和斯皮尔曼等级相关分析（显著性水平p < 0.05）。
该研究纳入了20名帕金森病患者（中位年龄：68.5岁）和20名非帕金森病患者（中位年龄：67岁）。两组在人口统计学、现存牙齿或咬合力测量方面未发现显著差异。在MVC咬合期间，帕金森病组咬肌的活动显著降低。帕金森病组在咀嚼时使用了其咬肌MVC的82%，而对照组使用了49%。此外，观察到帕金森病的严重程度与MVC张口期间的咬合力和二腹肌活动之间呈负相关。
这些发现表明，帕金森病可能会改变咀嚼肌在功能过程中的活动模式。这一新认识可用于设计有针对性的干预措施，旨在改善该患者群体的口面部功能。
