Immunoglobulin allotypes in patients with ankylosing spondylitis, Reiter's syndrome and acute anterior uveitis.

The immune response appears to be partially regulated by genes linked to the IgGH chain gene complex. Immunoglobulin allotypic markers Gm groups are distributed in Caucasians largely in 5 relatively well defined phenotypes. We examined the prevalence of these phenotypes in 119 patients with ankylosing spondylitis, Reiter's syndrome or acute anterior uveitis. No significant deviation from the control frequencies was noted.