Chen Heng, Xue Cong-Yang, Chen Shuang, Chen Zi-Ting, Tang Tian, Liu Xin, Xi Zhi-Peng, Kang Ran, Xie Lin
Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital on Integration of Chinese and Western Medicine Nanjing 210028, China Third Clinical Medical College, Nanjing University of Chinese Medicine Nanjing 210028, China.
Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital on Integration of Chinese and Western Medicine Nanjing 210028, China.
Zhongguo Zhong Yao Za Zhi. 2025 May;50(9):2596-2604. doi: 10.19540/j.cnki.cjcmm.20250210.501.
As one of the chronic diseases with high incidence in contemporary society, cervical spondylosis has increasing patient groups who gradually present a low age, and it seriously affects social and public health. Although modern medicine has made great progress in the pathological research and clinical treatment of cervical spondylosis, patients still face gastrointestinal side effects of nonsteroidal anti-inflammatory drugs(NSAIDs), neck pain, limited mobility, upper limb numbness, and other symptoms after conservative or surgical treatment. In the theory of traditional Chinese medicine(TCM), cervical spondylosis belongs to the categories of "Bi syndrome" "stiff neck" "stiff Bi", etc. With the change of the times, the change of lifestyle, and the application of western medicine treatment, the etiology and pathogenesis of TCM in cervical spondylosis also show new characteristics. In terms of etiology and pathogenesis, it involves the invasion of wind, cold, and dampness, long-term strain, liver and kidney deficiency, Qi and blood stasis, which are associated with factors such as cervical degeneration, muscle tension and spasm, intervertebral disc herniation, and nerve root compression in modern medicine. In terms of the evolution of pathogenesis, in the early stage, wind, cold, and dampness, were more common in Xuanfu, resulting in unfavorable muscles and bones, poor flow of Qi and blood, and cervical spondylosis and radiculopathy. Medium-term phlegm stasis and internal knots, sluggish muscles and veins, and long-term weathering and fire are more likely to occur in the vertebral artery and sympathetic radiculopathy. In the later stage, the positive Qi is depleted; the true Yin is damaged, and the viscera Qi and blood are deficient, which is most common in cervical myelopathy. The strategy of treating cervical spondylosis with TCM classic formulas applies Gegen Decoction, Wutou Decoction, Qianghuo Shengshi Decoction, Mahuang Jiazhu Decoction to patients with wind, cold, and dampness. Patients with phlegm dampness and blood stasis are treated with Huoxue Xiaoling Dan, Jinlingzi Powder, Siwu Decoction, Banxia Baizhu Tianma Decoction, Shuanghe Decoction, etc. For those patients with liver, spleen, and kidney deficiency, Huangqi Guizhi Wuwu Decoction, Tianma Gouteng Decoction, Guishao Dihuang Pills, Shenling Baizhu Powder, and Lizhong Decoction are used to invigorate the spleen, nourish Qi and blood, and tonify liver and kidney. In clinical practice, the authors advocate a safe and effective treatment plan of classic formulas based on deficiency and excess, the integration of formulas and syndromes, and the combination of modern research results, so as to relieve symptoms, reduce recurrence, and reduce medical burden.
颈椎病作为当代社会高发的慢性病之一,患者群体日益增多且逐渐呈现低龄化,严重影响社会公共卫生。尽管现代医学在颈椎病的病理研究和临床治疗方面取得了很大进展,但患者在保守或手术治疗后仍面临非甾体抗炎药的胃肠道副作用、颈部疼痛、活动受限、上肢麻木等症状。在中医理论中,颈椎病属于“痹证”“项强”“僵痹”等范畴。随着时代变迁、生活方式改变以及西医治疗的应用,中医对颈椎病的病因病机也呈现出新特点。在病因病机方面,涉及风寒湿邪侵袭、长期劳损、肝肾亏虚、气血瘀滞,这些与现代医学中的颈椎退变、肌肉紧张痉挛、椎间盘突出、神经根受压等因素相关。在病机演变方面,早期以风寒湿邪为主,多见于宣发不畅,导致筋骨不利、气血运行不畅,引发颈椎病及神经根病;中期痰瘀内结、筋脉迟缓,长期风化生火,多见于椎动脉及交感神经型颈椎病;后期正气亏虚、真阴受损,脏腑气血不足,多见于脊髓型颈椎病。中医经典方剂治疗颈椎病的策略,对于风寒湿型患者应用葛根汤、乌头汤、羌活胜湿汤、麻黄加术汤;对于痰湿血瘀型患者应用活血消灵丹、金铃子散、四物汤、半夏白术天麻汤、双合汤等;对于肝脾肾亏虚型患者应用黄芪桂枝五物汤、天麻钩藤饮、归芍地黄丸、参苓白术散、理中汤等,以健脾益气养血、滋补肝肾。在临床实践中,笔者主张基于虚实、方证结合、结合现代研究成果的安全有效的经典方剂治疗方案,以缓解症状、减少复发、减轻医疗负担。