Parker Richard, Arab Juan P, Lazarus Jeffrey V, Bataller Ramon, Singal Ashwani K
Leeds Liver Unit, St James's University Hospital, Leeds, UK.
Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Nat Rev Gastroenterol Hepatol. 2025 Jun 4. doi: 10.1038/s41575-025-01084-6.
Alcohol-related liver disease (ALD) is a major cause of morbidity and premature mortality around the world, with a substantial cost to individuals and to health-care systems. The incidence of ALD is closely associated with alcohol intake, and it is a preventable disease. There is clear evidence that public health measures to reduce alcohol consumption are effective, which in turn can have a positive effect on ALD. Effective policy includes controlling the price of alcohol, limiting or banning alcohol advertising and restricting the availability of alcohol. The strength of public health policy depends on the political willingness to develop robust strategies. However, effective lobbying of policy-makers by the alcohol industry and lack of political will are barriers to the implementation of these measures, resulting in suboptimal national alcohol control policies. Clinicians are well-placed to campaign for effective public health policy regarding alcohol to reduce the prevalence of ALD for the benefit of patients, their families and wider society. In this Perspective, we summarize the evidence for public health policies that affect alcohol consumption and the prevalence of ALD.
酒精性肝病（ALD）是全球发病和过早死亡的主要原因，给个人和医疗保健系统带来了巨大成本。ALD的发病率与酒精摄入量密切相关，且是一种可预防的疾病。有明确证据表明，减少酒精消费的公共卫生措施是有效的，这反过来又能对ALD产生积极影响。有效的政策包括控制酒精价格、限制或禁止酒精广告以及限制酒精的可获得性。公共卫生政策的力度取决于制定强有力战略的政治意愿。然而，酒精行业对政策制定者的有效游说以及缺乏政治意愿是实施这些措施的障碍，导致国家酒精控制政策不够理想。临床医生处于有利地位，可以为关于酒精的有效公共卫生政策开展宣传活动，以降低ALD的患病率，造福患者、其家人和更广泛的社会。在这篇观点文章中，我们总结了影响酒精消费和ALD患病率的公共卫生政策的证据。
