Elbana Ahmed, Saleh Wafaa, Youssef Jilan
Periodontology, Diagnosis, and Oral Radiology Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Mansoura City, Mansoura, 33516, Egypt.
BMC Oral Health. 2025 Jun 3;25(1):893. doi: 10.1186/s12903-025-06259-w.
The effectiveness of the modified coronally advanced tunnel (MCAT) technique in treating isolated gingival recession Type 1 (RT1) has been evaluated in a few studies. Hence, this prospective randomized controlled clinical trial was directed to assess the MCAT technique with connective tissue graft (CTG) or collagen matrix (CM) in improving clinical outcomes for isolated gingival recession type 1 (RT1), mainly the attached gingiva width (AGW) as a primary outcome. Despite the clinical relevance of AGW, there is a gap in the literature with limited studies concerning it as a primary outcome.
Forty patients were chosen and randomly assigned into either the control group (MCAT and CTG) or the test group (MCAT and CM) for short-term assessment (6 months) of single (RT1) gingival recession treatment. The primary outcomes were attached gingiva width (AGW), recession depth (RD), recession width (RW), and mean root coverage% (MRC%). The secondary outcomes included gingival thickness (GT), keratinized tissue width (KTW), periodontal probing depth (PPD), clinical attachment level (CAL), plaque index (PI), gingival index (GI), pink esthetic score (PES), root coverage esthetic score (RES), and patient-reported outcome measures (PROMs). The chi-square (χ²) test, Mann-Whitney U test, t-test, and Friedman test were used for statistical analysis of the outcomes.
Forty patients aged 18 to 45 years were enrolled in the current study. Evaluation of the primary outcomes (AGW, RD, RW) showed significant differences in the studied groups from the baseline to the final follow-up period (p-value ≤ 0.05). The MRC % results showed significant improvement after the 6-month follow-up period. For the control group, the MRC% was 97.08 ± 9.09, while for the test group, the MRC% was 96.75 ± 7.99. The PI, GI, PPD, CAL, KTW, PES, or RES values did not significantly differ among the two groups from the baseline to the final follow-up period.
Our study supported the efficacy of the MCAT in isolated gingival recession coverage. The CM may act as an alternative to CTG by increasing the patient's satisfaction and reducing tissue morbidity and surgical time.
The current clinical trial was retrospectively registered in ClinicalTrials.gov (ID: NCT06065774) and released on 11/18/2024.
在一些研究中已对改良冠向推进隧道（MCAT）技术治疗孤立性1型牙龈退缩（RT1）的有效性进行了评估。因此，这项前瞻性随机对照临床试验旨在评估采用结缔组织移植（CTG）或胶原基质（CM）的MCAT技术在改善孤立性1型牙龈退缩（RT1）的临床结局方面的效果，主要将附着龈宽度（AGW）作为主要结局指标。尽管AGW具有临床相关性，但作为主要结局指标的相关研究在文献中存在空白。
选择40例患者，随机分为对照组（MCAT和CTG）或试验组（MCAT和CM），对单一（RT1）牙龈退缩治疗进行短期评估（6个月）。主要结局指标为附着龈宽度（AGW）、退缩深度（RD）、退缩宽度（RW）和平均牙根覆盖百分比（MRC%）。次要结局指标包括牙龈厚度（GT）、角化组织宽度（KTW）、牙周探诊深度（PPD）、临床附着水平（CAL）、菌斑指数（PI）、牙龈指数（GI）、粉色美学评分（PES）、牙根覆盖美学评分（RES）以及患者报告的结局指标（PROMs）。采用卡方（χ²）检验、曼-惠特尼U检验、t检验和弗里德曼检验对结局进行统计分析。
本研究纳入了40例年龄在18至45岁之间的患者。对主要结局指标（AGW、RD、RW）的评估显示，从基线期到最终随访期，研究组之间存在显著差异（p值≤0.05）。MRC%结果显示，在6个月随访期后有显著改善。对照组的MRC%为97.08±9.09，而试验组的MRC%为96.75±7.99。从基线期到最终随访期，两组之间的PI、GI、PPD、CAL、KTW、PES或RES值无显著差异。
我们的研究支持MCAT在孤立性牙龈退缩覆盖方面的疗效。CM可作为CTG的替代方法，可提高患者满意度，减少组织损伤和手术时间。
本临床试验已在ClinicalTrials.gov上进行回顾性注册（ID：NCT06065774），并于2024年11月18日发布。
