Høvik Hedda, Jensen Knut Helge Midtbø, Børsting Torunn, Eftedal Randi Krog, Dahllöf Göran, Hafell Bjørnar, Fagerhaug Tone Natland, Lassemo Eva, Høiseth Marikken, Sen Abhijit, Skeie Marit S
Center for Oral Health Services and Research, Mid-Norway (TkMidt), Trondheim, Norway.
Oral Health Centre of Expertise in Western Norway (TkVest), Bergen, Norway.
BMC Oral Health. 2025 Jun 3;25(1):901. doi: 10.1186/s12903-025-06136-6.
Caries increment during adolescence, including enamel caries, is rarely explored in detail. This study assessed the caries increment during the period from 12 to 18 years. The specific objectives were to examine time trends, increment variability between individuals, and whether baseline caries experience at 12 years or sex had an impact on the caries increment.
The sample included seven birth cohorts (1996-2002; n = 23,135) from a general adolescent population in Trøndelag County, Norway. Data was based on dental records from the Public Dental Service. Two caries increment thresholds were examined at the tooth level: the enamel caries increment (ΔDT), and the caries increment at the dentin level, including missing and filled teeth (ΔDMFT). Zero-inflated Poisson models were used to account for the skewed distribution with a high proportion of zero caries increment (31.1% with ΔDT = 0 and 33.4% with ΔDMFT=0).
The mean caries increments for the seven cohorts were ΔDT = 3.14 (95% CI: 3.09-3.19) and ΔDMFT = 2.51 (95% CI: 2.47-2.55). A modest temporal trend of decreasing caries increment across cohorts was observed at both thresholds: ΔDT = -0.31 (95% CI: ±0.13) and ΔDMFT = -0.43 (95% CI: ±0.11). However, this decrease was small compared to the variation in caries increments between individuals. Females had slightly lower mean caries increment than males, but there was no effect of sex on the change across cohorts. Adolescents with high baseline caries experience at 12 years had higher mean caries increments compared to the intermediate or low baseline caries experience groups, and a reduction across cohorts was only seen in the two latter groups.
While there was a modest reduction in caries increment across cohorts, this reduction was small compared to the variation in caries increments between individuals. The change across cohorts was the same in females and males. Baseline caries experience at 12 years was a strong predictor of caries increment and the reduction across cohorts was only seen among those with lower baseline caries experience, incdicating an increased dental health disparity among Norwegian adolescents.
ClinicalTrials.gov ID: NCT05935813, Release Date: 28/06/2023.
青春期龋病进展,包括釉质龋,鲜少得到详细研究。本研究评估了12至18岁期间的龋病进展情况。具体目标是研究时间趋势、个体间进展差异,以及12岁时的基线龋病经历或性别是否对龋病进展有影响。
样本包括来自挪威特隆赫姆郡普通青少年人群的7个出生队列(1996 - 2002年;n = 23135)。数据基于公共牙科服务机构的牙科记录。在牙齿层面检查了两个龋病进展阈值:釉质龋进展(ΔDT),以及牙本质层面的龋病进展,包括缺失和充填牙(ΔDMFT)。采用零膨胀泊松模型来处理龋病进展为零比例较高的偏态分布(ΔDT = 0时为31.1%,ΔDMFT = 0时为33.4%)。
七个队列的平均龋病进展为ΔDT = 3.14(95%置信区间:3.09 - 3.19)和ΔDMFT = 2.51(95%置信区间:2.47 - 2.55)。在两个阈值下均观察到各队列间龋病进展呈适度下降的时间趋势:ΔDT = -0.31(95%置信区间:±0.13)和ΔDMFT = -0.43(95%置信区间:±0.11)。然而,与个体间龋病进展的差异相比,这种下降幅度较小。女性的平均龋病进展略低于男性,但性别对各队列间的变化无影响。12岁时基线龋病经历高的青少年,其平均龋病进展高于中度或低度基线龋病经历组,且各队列间的下降仅在后面两组中出现。
虽然各队列间龋病进展有适度下降,但与个体间龋病进展的差异相比,这种下降幅度较小。各队列间的变化在女性和男性中相同。12岁时的基线龋病经历是龋病进展的有力预测因素,且各队列间的下降仅在基线龋病经历较低者中出现,这表明挪威青少年的口腔健康差距在加大。
ClinicalTrials.gov标识符:NCT05935813,发布日期:2023年6月28日。